[HTML][HTML] Monitoring plasma levels of ganciclovir in AIDS patients receiving oral ganciclovir as maintenance therapy for CMV retinitis

C Piketty, C Bardin, J Gilquin, A Gairard… - Clinical microbiology …, 2000 - Elsevier
Objective To investigate whether low ganciclovir serum levels in patients on maintenance
oral ganciclovir therapy are associated with recurrence of CMV retinitis. Methods A …

Cytomegalovirus retinitis in AIDS patients: a comparative study of intravenous and oral ganciclovir as maintenance therapy

SA Danner, S Matheron - AIDS, 1996 - journals.lww.com
Objectives: To compare the safety and efficacy of oral ganciclovir with intravenous
ganciclovir for the maintenance therapy of cytomegalovirus (CMV) retinitis in AIDS patients …

Cytomegalovirus polymerase chain reaction viraemia in patients receiving ganciclovir maintenance therapy for retinitis

FE Bowen, VC Emery, P Wilson, MA Johnson… - Aids, 1998 - journals.lww.com
Objectives: To determine whether recurrence of polymerase chain reaction (PCR) viraemia
during maintenance ganciclovir for cytomegalovirus (CMV) retinitis correlates with (i) CMV …

High dose oral ganciclovir treatment for cytomegalovirus retinitis

JP Lalezari, DN Friedberg, J Bissett, MF Giordano… - Journal of clinical …, 2002 - Elsevier
Background: The oral formulation of ganciclovir is approved at a dose of 3.0 g/day for
maintenance treatment of cytomegalovirus (CMV) retinitis following an initial induction …

Oral ganciclovir for cytomegalovirus retinitis in patients with AIDS: results of two randomized studies

KE Squires - Aids, 1996 - journals.lww.com
Objective: To determine the relative effectiveness of an oral formulation compared to a
standard intravenous regimen of ganciclovir in preventing the progression of …

Oral ganciclovir as maintenance treatment for cytomegalovirus retinitis in patients with AIDS

WL Drew, D Ives, JP Lalezari… - … England Journal of …, 1995 - Mass Medical Soc
Background Cytomegalovirus retinitis, a sight-threatening infection associated with the
acquired immunodeficiency syndrome (AIDS), currently requires lifelong intravenous …

Randomized prospective trial of ganciclovir maintenance therapy for cytomegalovirus retinitis

MA Jacobson, JJ O'Donnell, HR Brodie… - Journal of medical …, 1988 - Wiley Online Library
We report the first randomized prospective comparative study of long‐term maintenance
ganciclovir (9‐[2‐hydroxy‐1‐(hydroxymethyl) ethoxymethyl] guanine, BW759U, DHPG) …

Pharmacokinetic, safety, and antiviral profiles of oral ganciclovir in persons infected with human immunodeficiency virus: a phase I/II study

SA Spector, DF Busch, S Follansbee… - Journal of Infectious …, 1995 - academic.oup.com
Abstract A phase I/II study evaluated the pharmacokinetics, tolerability, and antiviral activity
of oral ganciclovir in persons infected with human immunodeficiency virus (HIV). Oral …

Cytomegalovirus retinitis in AIDS patients: influence of cytomegaloviral load on response to ganciclovir, time to recurrence and survival

FE Bowen, P Wilson, A Cope, C Sabin, P Griffiths… - Aids, 1996 - journals.lww.com
Objectives: Despite life-long maintenance therapy, cytomegalovirus (CMV) retinitis
frequently progresses in patients with AIDS. Virological markers that could clarify …

Ganciclovir absolute bioavailability and steady-state pharmacokinetics after oral administration of two 3000-mg/d dosing regimens in human immunodeficiency virus …

RD Anderson, KG Griffy, D Jung, A Door, JD Hulse… - Clinical …, 1995 - Elsevier
Oral ganciclovir has recently been approved for use in long-term maintenance therapy in the
treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients. Although oral …