[HTML][HTML] Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors

Z Liu, H Wang, Z Li, RJ Dress, Y Zhu, S Zhang… - Immunity, 2023 - cell.com
Conventional dendritic cells (cDCs) are professional antigen-presenting cells that control the
adaptive immune response. Their subsets and developmental origins have been intensively …

[HTML][HTML] Transcriptional and functional analysis of CD1c+ human dendritic cells identifies a CD163+ subset priming CD8+ CD103+ T cells

P Bourdely, G Anselmi, K Vaivode, RN Ramos… - Immunity, 2020 - cell.com
Dendritic cells (DCs) are antigen-presenting cells controlling T cell activation. In humans, the
diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here …

CX3CR1+ CD8α+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells

L Bar-On, T Birnberg, KL Lewis… - Proceedings of the …, 2010 - National Acad Sciences
Lymphoid organs are characterized by a complex network of phenotypically distinct dendritic
cells (DC) with potentially unique roles in pathogen recognition and immunostimulation …

Subsets of CD1c+ DCs: Dendritic Cell Versus Monocyte Lineage

L Heger, TP Hofer, V Bigley, IJM de Vries… - Frontiers in …, 2020 - frontiersin.org
Currently three bona fide dendritic cell (DC) types are distinguished in human blood. Herein
we focus on type 2 DCs (DC2s) and compare the three defining markers CD1c, CD172, and …

Deciphering the transcriptional network of the dendritic cell lineage

JC Miller, BD Brown, T Shay, EL Gautier, V Jojic… - Nature …, 2012 - nature.com
Although much progress has been made in the understanding of the ontogeny and function
of dendritic cells (DCs), the transcriptional regulation of the lineage commitment and …

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage

RJ Dress, CA Dutertre, A Giladi, A Schlitzer, I Low… - Nature …, 2019 - nature.com
Dendritic cells (DC) are currently classified as conventional DCs (cDCs) and plasmacytoid
DCs (pDCs). Through a combination of single-cell transcriptomic analysis, mass cytometry …

CD8α+ dendritic cells originate from the CD8α dendritic cell subset by a maturation process involving CD8α, DEC-205, and CD24 up-regulation

GM del Hoyo, P Martı́n, CF Arias… - Blood, The Journal …, 2002 - ashpublications.org
CD8α+ and CD8α− dendritic cells (DCs) have been considered as independent DC
subpopulations both ontogenetically and functionally during recent years. However, it has …

Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells

J Feng, JN Pucella, G Jang, M Alcántara-Hernández… - Immunity, 2022 - cell.com
Developmental origins of dendritic cells (DCs) including conventional DCs (cDCs,
comprising cDC1 and cDC2 subsets) and plasmacytoid DCs (pDCs) remain unclear. We …

Relationships among murine CD11chigh dendritic cell subsets as revealed by baseline gene expression patterns

AD Edwards, D Chaussabel, S Tomlinson… - The Journal of …, 2003 - journals.aai.org
The functional relationships and properties of different subtypes of dendritic cells (DC)
remain largely undefined. To better characterize these cells, we used global gene analysis …

Development of CD8α-positive dendritic cells from a common myeloid progenitor

D Traver, K Akashi, M Manz, M Merad, T Miyamoto… - Science, 2000 - science.org
Dendritic cells (DCs) are critical in both initiating adaptive immune responses and
maintaining tolerance to self antigens. These apparently contradictory roles have been …