The mechanisms underlying the genesis and maintenance of T cell memory remain unclear.
In this study, we examined the evolution of a complex, antigen-specific T cell population …

Three distinct subsets of antigen‐experienced CD8+ T cells have been identified so far:
short‐living effector T cells (TEC) and two long‐living subsets, described as central (TCM) …

Listeria monocytogenes is an intracellular bacterium that elicits complex cytotoxic T-
lymphocyte (CTL) responses in infected mice. The responses of CTL populations that differ …

Helper T cells are critical for protective immunity, CD8+ T-cell memory, and CD4+ recall
responses, but whether the same or distinct CD4+ T cells are involved in these responses …

Memory CD8 T cells play a critical role in providing protection to immune hosts by
orchestrating rapid elimination of pathogen-infected cells after re-infection. Systemic …

The T cell response to infection consists of clonal expansion of effector cells, followed by
contraction to memory levels. It was previously thought that the duration of infection …

Induction and maintenance of T cell memory is critical for the control of intracellular
pathogens and tumors. Memory T cells seem to require few “maintenance signals,” though …

The immune response against the intracellular bacterium Listeria monocytogenes involves
both CD4+ and CD8+ T cells. We used the MHC class II-presented peptide listeriolysin 189 …

Mice that survived an immunizing infection with Listeria monocytogenes remained
specifically resistant to lethal secondary infection for several months. This acquired, long …

The intestinal mucosal CD8 T cell response to infection with Listeria monocytogenes was
measured using MHC class I tetramers and was compared with the response in peripheral …