The apolipoprotein multigene family: structure, expression, evolution, and molecular genetics
L Chan - Klinische Wochenschrift, 1989 - Springer
The plasma apolipoproteins can be classified into two subgroups: the soluble
apolipoproteins including apolipoprotein (apo) AI, A-II, A-IV, CI, C-II, C-III, and E, and the …
apolipoproteins including apolipoprotein (apo) AI, A-II, A-IV, CI, C-II, C-III, and E, and the …
[HTML][HTML] Identification of a negative regulatory region 5'of the human apolipoprotein B promoter.
B Paulweber, AR Brooks, BP Nagy… - Journal of Biological …, 1991 - Elsevier
We have identified a negative regulatory region between positions-1802 and-3211 of the
human apolipoprotein B gene that reduces expression of the gene. This “reducer” effect was …
human apolipoprotein B gene that reduces expression of the gene. This “reducer” effect was …
Genetic factors controlling structure and expression of apolipoproteins B and E in mice.
AJ Lusis, BA Taylor, D Quon, S Zollman… - Journal of Biological …, 1987 - ASBMB
We report the identification and partial characterization of polymorphisms among inbred
strains of mice affecting several aspects of the expression of apolipoproteins B and E (apoB …
strains of mice affecting several aspects of the expression of apolipoproteins B and E (apoB …
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
BA Laffitte, JJ Repa, SB Joseph… - Proceedings of the …, 2001 - National Acad Sciences
Apolipoprotein E (apoE) secreted by macrophages in the artery wall exerts an important
protective effect against the development of atherosclerosis, presumably through its ability to …
protective effect against the development of atherosclerosis, presumably through its ability to …
Pleiotropy and heterogeneity in the expression of atherogenic lipoproteins: the IRAS Family Study
JE Hokanson, CD Langefeld, BD Mitchell, LA Lange… - Human Heredity, 2003 - karger.com
Objective: Dyslipidemia is an important determinant of coronary disease. Phenotypic
correlations between atherogenic lipids are well established, but the contribution of common …
correlations between atherogenic lipids are well established, but the contribution of common …
Interaction of oestrogen and peroxisome proliferator-activated receptors with apolipoprotein (a) gene enhancers
LH Puckey, BL Knight - Biochemical Journal, 2002 - portlandpress.com
A high plasma concentration of lipoprotein (a)[Lp (a)] confers an increased risk for the
development of coronary heart disease. Hormones, such as oestrogen, are some of the few …
development of coronary heart disease. Hormones, such as oestrogen, are some of the few …
High-density lipoprotein: gene-based approaches to the prevention of atherosclerosis
JX Rong, EA Fisher - Annals of medicine, 2000 - Taylor & Francis
Although the atheroprotective role of high-density lipoprotein (HDL) has been well
documented in epidemiological and animal studies, highly effective therapeutic approaches …
documented in epidemiological and animal studies, highly effective therapeutic approaches …
Glucocorticoid increases rat apolipoprotein AI promoter activity
AH Taylor, J Raymond, JM Dionne, J Romney… - Journal of lipid …, 1996 - ASBMB
The observation that glucocorticoids increase the abundance of apolipoprotein AI led us to a
search for potential underlying mechanism (s). In this report, we show that the synthetic …
search for potential underlying mechanism (s). In this report, we show that the synthetic …
Modulation of apolipoprotein D and apolipoprotein E mRNA expression by growth arrest and identification of key elements in the promoter
S Do Carmo, D Séguin, R Milne, E Rassart - Journal of Biological Chemistry, 2002 - ASBMB
Apolipoprotein D (apoD) and apolipoprotein E (apoE) are co-expressed in many tissues,
and, in certain neuropathological situations, their expression appears to be under …
and, in certain neuropathological situations, their expression appears to be under …
Molecular biology of atherosclerosis
PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …