New therapeutic approaches to the prevention and treatment of atherosclerotic
cardiovascular disease (ASCVD) are needed. Plasma levels of high-density lipoprotein …

The identification of the binding sites for liver nuclear proteins present in the enhancer that
control the cell specific transcription of the human apolipoprotein AII gene is reported. Five …

In this work, we explored the existence of genetic variants within the apolipoprotein E gene
transcriptional regulatory region, using a denaturing gradient gel electrophoresis screening …

The apolipoprotein multigene family: biosynthesis, structure, structure-function relationships,
and evolution. - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …

Apolipoprotein B is a large, amphipathic protein that plays a central role in lipoprotein
metabolism. Because its overproduction and deficiency leads to metabolic and pathologic …

We have used apolipoprotein genes to investigate the signal transduction mechanisms
involved in the control of intestinal specific gene expression. The human apoAI, apoCIII, and …

In human, the gene coding for apolipoprotein AI (apo AI), a protein of the plasma lipid
transport system, is expressed only in the liver and the intestine. A naturally occurring A to G …

Therapeutic intervention for atherosclerosis has predominantly concentrated on regulating
cholesterol levels; however, these therapeutics are not efficacious for all patients …

A promoter polymorphism A/G at position 78 bp upstream of the transcription initiation site
characterizes the human apolipoprotein AI gene. Some studies correlated the higher Apo AI …

To investigate the mechanisms controlling tissue-specific expression of the human
apolipoprotein (apo) E/CI gene locus, human apoE and apoC-I gene constructs containing …