Selenium and the regulation of cell signaling, growth, and survival: molecular and mechanistic aspects

RC McKenzie, JR Arthur, GJ Beckett - Antioxidants and Redox …, 2002 - liebertpub.com
In the past 30 years, it has been recognized that dietary selenium (Se) is essential for the
normal function of many of the systems of the body. Furthermore, low Se intake can have …

[HTML][HTML] Selenium transport mechanism via selenoprotein P—Its physiological role and related diseases

Y Saito - Frontiers in Nutrition, 2021 - frontiersin.org
Selenoprotein P (SELENOP) is selenium (Se)-containing protein in plasma, which is
primarily produced in the liver. The “P” in SELENOP originated from the presence in plasma …

Selenoproteins: the key factor in selenium essentiality. State of the art analytical techniques for selenoprotein studies

IL Heras, M Palomo, Y Madrid - Analytical and bioanalytical chemistry, 2011 - Springer
Selenium is an essential element for human health. The benefits of selenium are many
including protection against cancer, heart diseases and other cardiovascular and muscle …

Selenium and selenoproteins in health and disease

LV Papp, A Holmgren, KK Khanna - Antioxidants & redox signaling, 2010 - liebertpub.com
The beneficial role of the trace element selenium (Se) in human health has been known for
several decades and is attributed both to low-molecular-weight Se compounds and to its …

[HTML][HTML] Selenium in human health and gut microflora: bioavailability of selenocompounds and relationship with diseases

RLU Ferreira, KCM Sena-Evangelista… - Frontiers in …, 2021 - frontiersin.org
This review covers current knowledge of selenium in the dietary intake, its bioavailability,
metabolism, functions, biomarkers, supplementation and toxicity, as well as its relationship …

[HTML][HTML] Selenium in bodily homeostasis: hypothalamus, hormones, and highways of communication

P Toh, JL Nicholson, AM Vetter, MJ Berry… - International journal of …, 2022 - mdpi.com
The ability of the body to maintain homeostasis requires constant communication between
the brain and peripheral tissues. Different organs produce signals, often in the form of …

Selenoproteins: Antioxidant selenoenzymes and beyond

H Steinbrenner, B Speckmann, LO Klotz - Archives of Biochemistry and …, 2016 - Elsevier
Adequate intake of the essential trace element and micronutrient selenium is thought to be
beneficial for maintaining human health. Selenium may modulate a broad spectrum of key …

[HTML][HTML] Historical roles of selenium and selenoproteins in health and development: the good, the bad and the ugly

PA Tsuji, D Santesmasses, BJ Lee… - International journal of …, 2021 - mdpi.com
Selenium is a fascinating element that has a long history, most of which documents it as a
deleterious element to health. In more recent years, selenium has been found to be an …

[HTML][HTML] Selenium, selenoproteins, and immunity

JC Avery, PR Hoffmann - Nutrients, 2018 - mdpi.com
Selenium is an essential micronutrient that plays a crucial role in development and a wide
variety of physiological processes including effect immune responses. The immune system …

Eukaryotic selenoproteins and selenoproteomes

AV Lobanov, DL Hatfield, VN Gladyshev - Biochimica et Biophysica Acta …, 2009 - Elsevier
Selenium is an essential trace element for which both beneficial and toxic effects in human
health have been described. It is now clear that the importance of having adequate amounts …