Selenium and selenoproteins: an overview on different biological systems

E Mangiapane, A Pessione… - Current Protein and …, 2014 - ingentaconnect.com
Selenium (Se) is an essential trace element for humans, plants and microorganisms.
Inorganic selenium is present in nature in four oxidation states: selenate, selenite, elemental …

[HTML][HTML] Trace element selenium effectively alleviates intestinal diseases

R Ye, J Huang, Z Wang, Y Chen, Y Dong - International Journal of …, 2021 - mdpi.com
Selenium (Se) is an essential trace element in the body. It is mainly used in the body in the
form of selenoproteins and has a variety of biological functions. Intestinal diseases caused …

Expression of selenoproteins in various rat and human tissues and cell lines

I Dreher, C Schmutzler, F Jakob, J Köhrle - Journal of trace elements in …, 1997 - Elsevier
Various rat and human tissues and cell lines naturally exposed to endogenous or
exogenous oxidative stress were examined for their pattern of selenoprotein transcripts …

[HTML][HTML] Effects of different selenium levels on gene expression of a subset of selenoproteins and antioxidative capacity in mice

Q Zhang, L Chen, K Guo, L Zheng, B Liu, W Yu… - Biological trace element …, 2013 - Springer
This study aimed to evaluate how excess selenium induces oxidative stress by determining
antioxidant enzyme activity and changes in expression of selected selenoproteins in mice …

[HTML][HTML] Selenium as a bioactive micronutrient in the human diet and its cancer chemopreventive activity

D Radomska, R Czarnomysy, D Radomski… - Nutrients, 2021 - mdpi.com
This review answers the question of why selenium is such an important trace element in the
human diet. Daily dietary intake of selenium and its content in various food products is …

Selenoproteins and protection against oxidative stress: selenoprotein N as a novel player at the crossroads of redox signaling and calcium homeostasis

S Arbogast, A Ferreiro - Antioxidants & redox signaling, 2010 - liebertpub.com
Healthy cells continually produce low levels of reactive oxygen species (ROS), which are
buffered by multiple antioxidant systems. Imbalance between ROS production and …

[HTML][HTML] Accessing human selenoproteins through chemical protein synthesis

L Dery, PS Reddy, S Dery, R Mousa, O Ktorza… - Chemical …, 2017 - pubs.rsc.org
The human body contains 25 selenoproteins, which contain in their sequence the twenty-
first encoded amino acid, selenocysteine. About a dozen of these proteins remain …

Selenium in biology: facts and medical perspectives

J Köhrle, R Brigelius-Flohé, A Böck, R Gärtner… - 2000 - degruyter.com
Several decades after the discovery of selenium as an essential trace element in vertebrates
approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the …

Structure–function relations, physiological roles, and evolution of mammalian ER-resident selenoproteins

VA Shchedrina, Y Zhang, VM Labunskyy… - Antioxidants & redox …, 2010 - liebertpub.com
Selenium is an essential trace element in mammals. The major biological form of this
micronutrient is the amino acid selenocysteine, which is present in the active sites of …

The antioxidant role of selenium and seleno-compounds

H Tapiero, DM Townsend, KD Tew - Biomedicine & pharmacotherapy, 2003 - Elsevier
Selenium (Se) is an essential trace element for animals and humans that is obtained from
dietary sources including cereals, grains and vegetables. The Se content of plants varies …