Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture
CS Hoefig, K Renko, J Köhrle, M Birringer… - The Journal of nutritional …, 2011 - Elsevier
The essential micronutrient selenium (Se) exerts its biological effects mainly through
enzymatically active selenoproteins. Their biosynthesis depends on the 21st proteinogenic …
enzymatically active selenoproteins. Their biosynthesis depends on the 21st proteinogenic …
Prooxidant mechanisms of selenium toxicity–a review
Selenium is an essential trace element in living organisms as integral part of seleno-
enzymes. However, excess amount of selenium is toxic for so-called non-accumulator …
enzymes. However, excess amount of selenium is toxic for so-called non-accumulator …
Se deficiency induces renal pathological changes by regulating selenoprotein expression, disrupting redox balance, and activating inflammation
S Li, Q Zhao, K Zhang, W Sun, X Jia, Y Yang, J Yin… - Metallomics, 2020 - academic.oup.com
Selenium (Se) is closely associated with kidney disease, and renal injury often occurs
together with hyposelenemia. This study was designed to reveal the mechanism underlying …
together with hyposelenemia. This study was designed to reveal the mechanism underlying …
Impact of dietary selenium intake on cardiac health: experimental approaches and human studies
S Tanguy, S Grauzam, J de Leiris… - Molecular nutrition & …, 2012 - Wiley Online Library
Selenium, a dietary trace mineral, essential for humans and animals, exerts its effects mainly
through its incorporation into selenoproteins. Adequate selenium intake is needed to …
through its incorporation into selenoproteins. Adequate selenium intake is needed to …
Regulation of selenocysteine content of human selenoprotein P by dietary selenium and insertion of cysteine in place of selenocysteine
AA Turanov, RA Everley, S Hybsier, K Renko… - PloS one, 2015 - journals.plos.org
Selenoproteins are a unique group of proteins that contain selenium in the form of
selenocysteine (Sec) co-translationally inserted in response to a UGA codon with the help of …
selenocysteine (Sec) co-translationally inserted in response to a UGA codon with the help of …
Selenium and chronic diseases: a nutritional genomics perspective
C Méplan - Nutrients, 2015 - mdpi.com
Mechanistic data have revealed a key role for selenium (Se) and selenoproteins in
biological pathways known to be altered in multifactorial diseases, such as cellular …
biological pathways known to be altered in multifactorial diseases, such as cellular …
Role of selenium-containing proteins in T-cell and macrophage function
BA Carlson, MH Yoo, RK Shrimali, R Irons… - Proceedings of the …, 2010 - cambridge.org
Selenium (Se) has been known for many years to have played a role in boosting the
immune function, but the manner in which this element acts at the molecular level in host …
immune function, but the manner in which this element acts at the molecular level in host …
Mechanisms by which selenium influences immune responses
PR Hoffmann - Archivum immunologiae et therapiae experimentalis, 2007 - Springer
Selenium (Se) is an essential dietary trace element that influences immune responses
through its incorporation into selenoproteins as the amino acid selenocysteine. This review …
through its incorporation into selenoproteins as the amino acid selenocysteine. This review …
Elemental selenium at nano size (Nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: comparison with se-methylselenocysteine in …
J Zhang, X Wang, T Xu - Toxicological sciences, 2008 - academic.oup.com
Selenium (Se) is an essential trace element with a narrow margin between beneficial and
toxic effects. As a promising chemopreventive agent, its use requires consumption over the …
toxic effects. As a promising chemopreventive agent, its use requires consumption over the …
Selenium in human health and disease: An overview
R Brigelius-Flohé - Selenium, 2018 - Springer
Since its detection in 1817 selenium underwent an adventurous trip from a toxic to an
essential element. As integral part of selenoproteins it was assumed that it is capable to …
essential element. As integral part of selenoproteins it was assumed that it is capable to …