[HTML][HTML] Synthesis and in vitro evaluation of new nitro-substituted thiazolyl hydrazone derivatives as anticandidal and anticancer agents

MD Altıntop, A Özdemir, G Turan-Zitouni, S Ilgın, Ö Atlı… - Molecules, 2014 - mdpi.com
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their
anticandidal activity using a broth microdilution assay. Among the synthesized compounds …

Synthesis and evaluation of new thiazolyl hydrazone derivatives as potential anticancer agents

Z Asım Kaplancıklı, B Sever… - Letters in Drug …, 2017 - ingentaconnect.com
Background: In recent years, thiazole derivatives incorporated with hydrazone moiety have
attracted a great deal of interest due to their pivotal role in the field of current cancer …

Synthesis, anti-Candida activity, and cytotoxicity of new (4-(4-iodophenyl) thiazol-2-yl) hydrazine derivatives

D Secci, B Bizzarri, A Bolasco, S Carradori… - European journal of …, 2012 - Elsevier
Novel (4-(4-iodophenyl)-thiazol-2-yl) hydrazine derivatives were assayed for their in vitro
anti-Candida activity, compared to topical and systemic antifungal drugs, against twenty …

Synthesis and biological evaluation of new quinoline-based thiazolyl hydrazone derivatives as potent antifungal and anticancer agents

A Erguc, MD Altintop, O Atli, B Sever… - Letters in Drug …, 2018 - ingentaconnect.com
Background: In medicinal chemistry, thiazoles have gained great importance in antifungal
and anticancer drug design and development. Objectives: The aim of this study was to …

Synthesis and biological evaluation of thiazolyl-ethylidene hydrazino-thiazole derivatives: a novel heterocyclic system

LA Al-Mutabagani, FM Abdelrazek, SM Gomha… - Applied Sciences, 2021 - mdpi.com
The reaction of 2-(1-(2-(2-(4-methoxybenzylidene) hydrazinyl)-4-methylthiazol-5-yl)
ethylidene) hydrazinecarbothioamide with a range of hydrazonoyl chlorides and α-halo …

Synthesis and biological evaluation of novel 2, 4-disubstituted-1, 3-thiazoles as anti-Candida spp. agents

F Chimenti, B Bizzarri, A Bolasco, D Secci… - European journal of …, 2011 - Elsevier
A new series of [4-(4′-substituted-phenyl) thiazol-2-yl] hydrazine derivatives were
synthesized in good yield (86–99%) and characterized by elemental analysis, IR, 1H NMR …

Studies on hydrazone derivatives as antifungal agents

A Özdemir, G Turan-Zitouni… - Journal of Enzyme …, 2008 - Taylor & Francis
The increasing clinical importance of drug-resistant fungal pathogens has urged additional
need to fungal research and new antifungal compound development. For this purpose …

Facile synthesis and biological assays of novel 2, 4-disubstituted hydrazinyl-thiazoles analogs

F Ghanbari Pirbasti, NO Mahmoodi - Molecular diversity, 2016 - Springer
A convenient, one-pot multi-component synthesis of new 2, 4-disubstituted hydrazinyl-
thiazoles was accomplished using different aldehydes/ketones, thiosemicarbazide, and 4 …

Synthesis and cytotoxicity of novel (thiazol-2-yl) hydrazine derivatives as promising anti-Candida agents

S Carradori, D Secci, A Bolasco, D Rivanera… - European Journal of …, 2013 - Elsevier
Abstract Thirty-eight new (4-(4-substituted-phenyl/2, 4-disubstituted-phenyl)-thiazol-2-yl)
hydrazine derivatives were synthesized in good yield and assayed for their in vitro anti …

Design, and synthesis of selectively anticancer 4-cyanophenyl substituted thiazol-2-ylhydrazones

H Mehmood, M Musa, S Woodward, MS Hossan… - RSC …, 2022 - pubs.rsc.org
Cyclization of substituted thiosemicarbazones with α-bromo-4-cyanoacetophenone allows
rapid single-step sustainable syntheses of 4-cyanophenyl-2-hydrazinylthiazoles libraries (30 …