A series of novel pyrazolo [3, 4-b] pyridine based target compounds were synthesized
starting from the key intermediate ethyl 2-(3-amino-6-(trifluoromethyl)-1 H-pyrazolo [3, 4-b] …

Objectives Cancer is one of the leading causes of death throughout the world. Current
therapy options suffer from the major limitations of side effects and drug resistance. Thus …

Abstract Background Thiazoles and 1, 3, 4-thiadiazoles have been reported to possess
various pharmacological activities. Results A novel series of thiazoles carrying 1, 3, 4 …

In this study, a series of novel 1, 2, 4-triazolo-[3, 4-b]-1, 3, 4-thiadiazole (6a–g) and 1, 3, 4-
oxadiazole (7a–g, 8) were synthesized from N-(6-chlorobenzo [d] thiazol-2-yl) hydrazine …

Thiazole and its derivatives have received a lot of attention from researchers due to its wide
biological, pharmacological, and anticancer properties. A novel series of 2-[2-[4-Hydroxy-3 …

Purpose: The aim of this article is to synthesize, characterize and evaluate the antimicrobial
activity of certain novel 3-methyl-5-oxo-4-(phenyl hydrazono)-4, 5-dihydro-pyrazol-1-yl] …

A series of 1, 3-benzothiazole-2-yl-hydrazones were synthesized and evaluated for
antibacterial activity against four different bacterial species and antifungal activity against …

Owing to the growing need for antifungal agents, we synthesized a new series 2-((5-(4-(5-
substituted-1 H-benzimidazol-2-yl) phenyl)-4-substituted-4 H-1, 2, 4-triazol-3-yl) thio)-1 …

The reaction of 2-cyano-3-(dimethylamino)-N-((2-methoxynaphthalen-1-yl) methylene)
acrylohydrazide (2) with some nitrogen nucleophiles, phenols and compounds, having an …

The synthesis and antifungal activity of a series of 2-nitroaryl-5-phenylsulfonyl-1, 3, 4-thiadia-
zoles (5a-e) are described. The in vitro antifungal activity of the compounds was determined …