The gut–brain axis (GBA) is the umbrella term to include all bidirectional communication
between the brain and gastrointestinal (GI) tract in the mammalian body. Evidence from over …

Previous studies have identified a crucial role of the gut microbiome in modifying
Alzheimer's disease (AD) progression. However, the mechanisms of microbiome–brain …

Intestinal microbiota has its role as an important component of human physiology. It
produces metabolites that module key functions to establish a symbiotic crosstalk with their …

Alzheimer's disease (AD) is a neurodegenerative disorder with poorly understood etiology.
AD has several similarities with other “Western lifestyle” inflammatory diseases, where the …

Emerging evidence supports that the gut microbiome, reconsidered as a new organ in the
human body, can not only affect the local gut, but also communicate with the brain via …

The human gut microbiota influences obesity, insulin resistance, and the subsequent
development of type 2 diabetes (T2D). The gut microbiota digests and ferments nutrients …

Over the past decade, the gut microbiota has emerged as an important frontier in
understanding the human body's homeostasis and the development of diseases. Gut flora in …

Previous studies have found that intracorporal short-chain fatty acids (SCFAs), as the main
metabolites of the gut microbiota, play important roles in the intestinal physiology and …

Background Cognitive impairment, an increasing mental health issue, is a core feature of the
aging brain and neurodegenerative diseases. Industrialized nations especially, have …

Alzheimer disease (AD) is the most common form of neurodegenerative disease in older
adults and has a complicated etiology. Recently, the roles of short-chain fatty acids (SCFAs) …