Gastrointestinal tract, microbiota and multiple sclerosis (MS) and the link between gut microbiota and CNS

B Yousefi, A Babaeizad, SZ Banihashemian… - Current …, 2023 - Springer
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by central nervous
system (CNS) lesions that can lead to severe neurological defects. Evidence is mounting …

Implications of diet and the gut microbiome in neuroinflammatory and neurodegenerative diseases

S Hirschberg, B Gisevius, A Duscha… - International journal of …, 2019 - mdpi.com
Within the last century, human lifestyle and dietary behaviors have changed dramatically.
These changes, especially concerning hygiene, have led to a marked decrease in some …

Brief exposure of neuronal cells to levels of SCFAs observed in human systemic circulation impair lipid metabolism resulting in apoptosis

TA Fillier, S Shah, KM Doody, TH Pham, I Aubry… - Scientific Reports, 2022 - nature.com
Communication between gut microbiota and the brain is an enigma. Alterations in the gut
microbial community affects enteric metabolite levels, such as short chain fatty acids …

Regulation of host energy metabolism by gut microbiota-derived short-chain fatty acids

H Shimizu, R Ohue-Kitano, I Kimura - Glycative Stress Research, 2019 - jstage.jst.go.jp
The gut microbiota is attracting attention as a new target for preventing and improving
metabolic diseases, including obesity and type 2 diabetes mellitus. About 100 trillion or …

The role of short-chain fatty acids in microbiota–gut–brain communication

B Dalile, L Van Oudenhove, B Vervliet… - Nature reviews …, 2019 - nature.com
Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of
dietary fibre in the gastrointestinal tract, are speculated to have a key role in microbiota–gut …

From gut microbiota dysfunction to obesity: could short-chain fatty acids stop this dangerous course?

L Barrea, G Muscogiuri, G Annunziata, D Laudisio… - Hormones, 2019 - Springer
Study of the interactions between the gut microbiota and brain-gut axis represents a very
appealing approach to increasing our knowledge about the mechanisms leading to obesity …

Modulation of microbially derived short-chain fatty acids on intestinal homeostasis, metabolism, and neuropsychiatric disorder

S Xiao, S Jiang, D Qian, J Duan - Applied Microbiology and Biotechnology, 2020 - Springer
A diverse range of symbiotic gut bacteria codevelops with the host and is considered a
metabolic “organ” that not only facilitates harvesting of nutrients from the dietary components …

Short-chain fatty acids-producing probiotics: A novel source of psychobiotics

Y Cheng, J Liu, Z Ling - Critical reviews in food science and …, 2022 - Taylor & Francis
Psychobiotics—live microorganisms with potential mental health benefits, which can
modulate the microbiota-gut-brain-axis via immune, humoral, neural, and metabolic …

[PDF][PDF] Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases

EJ Gates, AK Bernath, A Klegeris - Reviews in the Neurosciences, 2022 - degruyter.com
The global prevalence of Alzheimer's disease and Parkinson's disease is steadily increasing
due to the aging population. The lack of effective drugs against these neurodegenerative …

Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation

M Kasubuchi, S Hasegawa, T Hiramatsu, A Ichimura… - Nutrients, 2015 - mdpi.com
During feeding, the gut microbiota contributes to the host energy acquisition and metabolic
regulation thereby influencing the development of metabolic disorders such as obesity and …