Gut-brain axis a key player to control gut Dysbiosis in neurological diseases

I Pan, PK Issac, MM Rahman, A Guru… - Molecular …, 2023 - Springer
Parkinson's disease is a chronic neuropathy characterised by the formation of Lewy bodies
(misfolded alpha-synuclein) in dopaminergic neurons of the substantia nigra and other parts …

Effect of short chain fatty acids on age-related disorders

MF Fernandes, S de Oliveira, M Portovedo… - Reviews on New Drug …, 2020 - Springer
Recent studies have indicated a prominent role of intestinal microbiota in regulation of
several physiological aspects of the host including development and activation of the …

Healthy gut, healthy brain: the gut microbiome in neurodegenerative disorders

S Chandra, MT Alam, J Dey… - Current topics in …, 2020 - ingentaconnect.com
Background: The central nervous system (CNS) known to regulate the physiological
conditions of human body, also itself gets dynamically regulated by both the physiological as …

Emerging role of gut microbiota dysbiosis in neuroinflammation and neurodegeneration

R Solanki, A Karande, P Ranganathan - Frontiers in Neurology, 2023 - frontiersin.org
Alzheimer's disease (AD), is a chronic age-related progressive neurodegenerative disorder,
characterized by neuroinflammation and extracellular aggregation of Aβ peptide …

Effects of gut microbiota on neurodegenerative diseases

S Khatoon, N Kalam, S Rashid, G Bano - Frontiers in Aging …, 2023 - frontiersin.org
A progressive degradation of the brain's structure and function, which results in a reduction
in cognitive and motor skills, characterizes neurodegenerative diseases (NDs) such as …

Unveiling the role of gut-brain axis in regulating neurodegenerative diseases: A comprehensive review

H Yadav, R Bhardwaj, A Bakshi, S Gupta, SK Maurya - Life Sciences, 2023 - Elsevier
Emerging evidence have shown the importance of gut microbiota in regulating brain
functions. The diverse molecular mechanisms involved in cross-talk between gut and brain …

Crosstalk between the gut microbiome and bioactive lipids: therapeutic targets in cognitive frailty

LC Baptista, Y Sun, CS Carter, TW Buford - Frontiers in nutrition, 2020 - frontiersin.org
Cognitive frailty is a geriatric condition defined by the coexistence of cognitive impairment
and physical frailty. This “composite” aging phenotype is associated with a higher risk of …

The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids

W Xiao, J Su, X Gao, H Yang, R Weng, W Ni, Y Gu - Microbiome, 2022 - Springer
Background Chronic cerebral hypoperfusion (CCH) underlies secondary brain injury
following certain metabolic disorders and central nervous system (CNS) diseases …

Effects of short chain fatty acids on metabolic and inflammatory processes in human health

W Campos-Perez, E Martinez-Lopez - … (BBA)-Molecular and Cell Biology of …, 2021 - Elsevier
Butyrate, propionate, and acetate are short-chain fatty acids (SCFAs) mainly produced by
bacterial metabolism in the human gut after dietary fiber intake. SCFAs are considered …

The role of gut microbiota and gut–brain interplay in selected diseases of the central nervous system

J Doroszkiewicz, M Groblewska, B Mroczko - International journal of …, 2021 - mdpi.com
The gut microbiome has attracted increasing attention from researchers in recent years. The
microbiota can have a specific and complex cross-talk with the host, particularly with the …