Understanding deficient elimination of uric acid

M Aringer, J Graessler - The Lancet, 2008 - thelancet.com
It usually takes decades to increase the body's urate storage to amounts at which uric acid
crystals precipitate and activate the NLRP3 inflammasome, 1 leading to a first attack of gout …

Attention—grapefruit!

LA Grande, RD Mendez, RT Krug, EJ Verschuyl - The Lancet, 2009 - thelancet.com
In November, 2008, a 42-year-old woman presented to our emergency department with
difficulty in walking, short ness of breath, and light-headedness. The day before, she had …

Gout: diet and uric acid revisited

ML Snaith - The Lancet, 2001 - thelancet.com
For personal use. Only reproduce with permission from The Lancet Publishing Group. Gout:
diet and uric acid revisited Page 1 For personal use. Only reproduce with permission from The …

Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England

CF Kuo, MJ Grainge, C Mallen, W Zhang, M Doherty - Jama, 2014 - jamanetwork.com
Methods| Approvals with a waiver of informed consent were obtained from the Trent
Multicenter Research Ethics Committee and the independent scientific advisory committee …

[引用][C] Lancet

KH Hong - 1990

Gout and hyperuricaemia: a worldwide health issue of joints and beyond

M Gamala, JWG Jacobs - Rheumatology, 2019 - academic.oup.com
In this issue of Rheumatology, Singh et al.[1] report from their observational cohort study
using the NHANES database the prevalence of reported gout and of hyperuricaemia among …

[HTML][HTML] Patients with gout: an under-recognised group at high risk of COVID-19

N Dalbeth, PC Robinson - The Lancet. Rheumatology, 2021 - ncbi.nlm.nih.gov
New Zealanders), and Pacific Peoples, and in non-Hispanic African Americans. Thus, the
ethnic disparities in COVID-19 outcomes for Indigenous peoples and African Americans are …

What is gout?

K Yip, J Berman - Jama, 2021 - jamanetwork.com
What Causes Gout? People with gout have high blood levels of uric acid, a substance
produced during digestion of certain foods and drinks (such as red meat, seafood, alcohol …

Variants predictive of risk of gout

P Sulem - US Patent App. 13/984,689, 2014 - Google Patents
0001 Gout is a medical condition characterized by recur rent attacks of acute inflammatory
arthritis. It is the most common cause of inflammatory arthritis among men and …

Should prednisolone be first-line therapy for acute gout?

P Richette, T Bardin - Lancet (London, England), 2008 - thelancet.com
Hein Janssens and colleagues (May 31, p 1854) 1 are to be commended for their
randomised trial that showed prednisolone to be as effective as naproxen for the treatment …