Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner
S Bachiller, I Hidalgo, MG Garcia… - Journal of …, 2022 - Springer
Background The risk of developing Alzheimer's disease (AD) is modulated by genetic and
environmental factors. Early-life stress (ELS) exposure during critical periods of brain …
environmental factors. Early-life stress (ELS) exposure during critical periods of brain …
Are there any cognitive and behavioral changes potentially related to quarantine due to the COVID-19 pandemic in people with mild cognitive impairment and AD …
M Tsatali, D Moraitou, E Poptsi, E Sia, C Agogiatou… - Brain sciences, 2021 - mdpi.com
The aim of the study was to examine potential cognitive, mood (depression and anxiety) and
behavioral changes that may be related to the quarantine and the lockdown applied during …
behavioral changes that may be related to the quarantine and the lockdown applied during …
[HTML][HTML] Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice
L Zhang, J Li, A Lin - STAR protocols, 2021 - Elsevier
Neuronal loss resulting from progressive neurodegeneration is a major pathological feature
of Alzheimer's disease (AD). Here, we present a protocol to detect neurodegeneration …
of Alzheimer's disease (AD). Here, we present a protocol to detect neurodegeneration …
Social isolation and the brain: effects and mechanisms
An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide
reduction in social interaction, which is associated with many adverse effects on health in …
reduction in social interaction, which is associated with many adverse effects on health in …
Reviews in cellular neurophysiology 2022: neurophysiological mechanisms in the aging brain
JL Plotkin, SM Graves, M Riessland - Frontiers in Cellular …, 2024 - frontiersin.org
The aging process of the human brain is deserving of significant attention due to the fact that
aging is a primary risk factor for numerous neurodegenerative disorders (Hou et al., 2019) …
aging is a primary risk factor for numerous neurodegenerative disorders (Hou et al., 2019) …
Early-life stress does not aggravate spatial memory or the process of hippocampal neurogenesis in adult and middle-aged APP/PS1 mice
L Hoeijmakers, A Amelianchik, F Verhaag… - Frontiers in Aging …, 2018 - frontiersin.org
Life-time experiences are thought to influence the risk to develop the neurodegenerative
disorder Alzheimer's disease (AD). In particular, early-life stress (ES) may modulate the …
disorder Alzheimer's disease (AD). In particular, early-life stress (ES) may modulate the …
Transcriptional, behavioral and biochemical profiling in the 3xTg-AD mouse model reveals a specific signature of amyloid deposition and functional decline in …
W Yin, N Cerda-Hernández… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD)-related degenerative decline is associated to the presence of
amyloid beta (Aβ) plaque lesions and neuro fibrillary tangles (NFT). However, the precise …
amyloid beta (Aβ) plaque lesions and neuro fibrillary tangles (NFT). However, the precise …
Evaluation of altered cell-cell communication between glia and neurons in the hippocampus of 3xTg-AD mice at two time points
Alzheimer's disease (AD) is the most common form of dementia and is characterized by
progressive memory loss and cognitive decline, affecting behavior, speech, and motor …
progressive memory loss and cognitive decline, affecting behavior, speech, and motor …
Early cognitive and behavioral deficits in mouse models for tauopathy and Alzheimer's disease
C Samaey, A Schreurs, S Stroobants… - Frontiers in aging …, 2019 - frontiersin.org
Neurocognitive disorders, among which Alzheimer's disease (AD), have become one of the
major causes of death in developed countries. No effective disease-modifying therapy is …
major causes of death in developed countries. No effective disease-modifying therapy is …
Resting-state neural dynamics changes in older adults with post-COVID syndrome and the modulatory effect of cognitive training and sex
B Nagy, AB Protzner, B Czigler, ZA Gaál - GeroScience, 2024 - Springer
Post-COVID syndrome manifests with numerous neurological and cognitive symptoms, the
precise origins of which are still not fully understood. As females and older adults are more …
precise origins of which are still not fully understood. As females and older adults are more …