Identification of a Grga-Euo-Hrca transcriptional regulatory network in Chlamydia
W Wurihan, Y Zou, AM Weber, K Weldon, Y Huang… - Msystems, 2021 - Am Soc Microbiol
Chlamydia trachomatis is an obligate intracellular bacterium whose unique developmental
cycle consists of an infectious elementary body and a replicative reticulate body …
cycle consists of an infectious elementary body and a replicative reticulate body …
Requirement of GrgA for Chlamydia infectious progeny production, optimal growth, and efficient plasmid maintenance
B Lu, Y Wang, W Wurihan, A Cheng, S Yeung… - Mbio, 2024 - Am Soc Microbiol
Chlamydia, an obligate intracellular bacterial pathogen, has a unique developmental cycle
involving the differentiation of invading elementary bodies (EBs) to noninfectious reticulate …
involving the differentiation of invading elementary bodies (EBs) to noninfectious reticulate …
GrgA overexpression inhibits Chlamydia trachomatis growth through sigma66-and sigma28-dependent mechanisms
W Wurihan, AM Weber, Z Gong, Z Lou, S Sun… - Microbial …, 2021 - Elsevier
The obligate intracellular bacterium Chlamydia trachomatis is an important human pathogen
with a biphasic developmental cycle comprised of an infectious elementary body (EB) and a …
with a biphasic developmental cycle comprised of an infectious elementary body (EB) and a …
Role for GrgA in Regulation of σ28-Dependent Transcription in the Obligate Intracellular Bacterial Pathogen Chlamydia trachomatis
M Desai, W Wurihan, R Di, JD Fondell… - Journal of …, 2018 - Am Soc Microbiol
The obligate intracellular bacterial pathogen Chlamydia trachomatis has a unique
developmental cycle consisting of two contrasting cellular forms. Whereas the primary …
developmental cycle consisting of two contrasting cellular forms. Whereas the primary …
Euo is a developmental regulator that represses late genes and activates midcycle genes in Chlamydia trachomatis
OR Hakiem, SMA Rizvi, C Ramirez, M Tan - Mbio, 2023 - Am Soc Microbiol
The pathogenic bacterium Chlamydia reproduces via an unusual intracellular
developmental cycle in which it converts from a dividing form (reticulate body or RB) to an …
developmental cycle in which it converts from a dividing form (reticulate body or RB) to an …
Diversity of σ66-Specific Promoters Contributes to Regulation of Developmental Gene Expression in Chlamydia trachomatis
L Shen, L Gao, Y Zhang, Z Hua - Journal of Bacteriology, 2023 - Am Soc Microbiol
Promoter recognition by the RNA polymerase (RNAP) holoenzyme is a key step in gene
regulation. In Chlamydia trachomatis, a medically important obligate intracellular bacterium …
regulation. In Chlamydia trachomatis, a medically important obligate intracellular bacterium …
Quantifying promoter activity during the developmental cycle of Chlamydia trachomatis
Y Cong, L Gao, Y Zhang, Y Xian, Z Hua, H Elaasar… - Scientific Reports, 2016 - nature.com
Chlamydia trachomatis is an important human pathogen that undergoes a characteristic
development cycle correlating with stage-specific gene expression profiles. Taking …
development cycle correlating with stage-specific gene expression profiles. Taking …
Chlamydial GroEL autoregulates its own expression through direct interactions with the HrcA repressor protein
AC Wilson, CC Wu, JR Yates III, M Tan - Journal of bacteriology, 2005 - Am Soc Microbiol
In the pathogenic bacterium Chlamydia trachomatis, a transcriptional repressor, HrcA,
regulates the major heat shock operons, dnaK and groE. Cellular stress causes a transient …
regulates the major heat shock operons, dnaK and groE. Cellular stress causes a transient …
Chlamydia trachomatis ChxR is a transcriptional regulator of virulence factors that function in in vivo host–pathogen interactions
Chlamydia trachomatis is an obligate intracellular pathogen characterized by a unique
biphasic developmental cycle that alternates between infectious and non-infectious …
biphasic developmental cycle that alternates between infectious and non-infectious …
Following the footsteps of chlamydial gene regulation
Regulation of gene expression ensures an organism responds to stimuli and undergoes
proper development. Although the regulatory networks in bacteria have been investigated in …
proper development. Although the regulatory networks in bacteria have been investigated in …