Ischemic heart disease is a common condition and a leading cause of mortality and
morbidity. Macrophages, besides their role in host defense and tissue homeostasis, are …

Cardiovascular diseases are the leading cause of mortality worldwide. It is widely known
that non-resolving inflammation results in atherosclerotic conditions, which are responsible …

Cardiovascular diseases, such as myocardial infarction (MI), are a leading cause of death
worldwide. Acute MI (AMI) inflicts massive injury to the coronary microcirculation, causing …

Although great advances have been made, the problem of irreversible myocardium loss due
to the limited regeneration capacity of cardiomyocytes has not been fully solved. The …

One of the most ambitious goals in modern cardiology is to regenerate the injured
myocardium. The human myocardium has poor regenerative power. Thus, significant …

Cardiac macrophages are abundant in the healthy heart and after myocardial infarction (MI).
Different macrophage phenotypes likely promote myocardial health vs. disease. Infarct …

The heart contains a population of resident macrophages that markedly expands following
injury through recruitment of monocytes and through proliferation of macrophages. In …

Emerging evidence points to the involvement of specialized cells of the immune system as
key drivers in the pathophysiology of cardiovascular diseases. Monocytes are an essential …

Myocardial infarction is the most common form of acute cardiac injury attributing to heart
failure. While there have been significant advances in current therapies, mortality and …

Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …