Background: Progress in molecular biology for the production of bispecific antibodies
(BiAbs) and the expanding knowledge on receptors on malignant and normal target cells …

Bispecific antibodies (bsAbs) are artificial antibodies with two distinct antigen-binding sites
that can bind to different antigens or different epitopes on the same antigen. Based on a …

ABSTRACT Introduction: Bispecific antibodies (BsAb) are emerging as a novel approach for
dual targeting strategies. Two bispecific antibodies are approved for therapy and> 30 are in …

In past years, both laboratory and early clinical studies have demonstrated that bispecific
antibodies (BsAbs) may have significant potential application in cancer therapy either by …

Bispecific antibodies (bsAbs) refer to a large family of molecules that recognize two different
epitopes or antigens. Although a series of challenges, especially immunogenicity and chain …

Immunotherapy has redefined the treatment of cancer patients and it is constantly
generating new advances and approaches. Among the multiple options of immunotherapy …

Recent progressions in immunotherapy have transformed cancer treatment, providing a
promising strategy that activates the immune system of the patient to find and eliminate …

Targeted cellular immunotherapy with bifunctional antibodies (bsAbs) has emerged as a
promising therapeutic approach for cancer over the last two decades. Progress in antibody …

With the development of molecular cloning technology and the deep understanding of
antibody engineering, there are diverse bispecific antibody formats from which to choose to …

Development of cancers mostly involves more than one signal pathways, because of the
complicated nature of cancer cells. As such, the most effective treatment option is the one …