Potent immunosuppressive and anti-inflammatory bisindole alkaloids from Melodinus fusiformis

L Liu, MJ Xie, WB Zhou, JT Wang, JY Wang… - Natural Product …, 2022 - Taylor & Francis
Phytochemical investigation of Melodinus fusiformis led to a new aspidosperma-
aspidosperma bisindole alkaloid (BIA), bis-19 β-hydroxyvenalstonidine (1), together with …

HRESIMS-guided isolation of aspidosperma-scandine type bisindole alkaloids from Melodinus cochinchinensis and their anti-inflammatory and cytotoxic activities

FR Li, L Liu, YP Liu, JT Wang, ML Yang, A Khan… - Phytochemistry, 2021 - Elsevier
The Melodinus species have been proved to be good resources of bisindole alkaloids. Six
bisindole alkaloids were isolated from the leaves and stems of Melodinus cochinchinensis …

Melaxillines A and B, monoterpenoid indole alkaloids from Melodinus axillaris

L Fang, SM Tian, J Zhou, YL Lin, ZW Wang, X Wang - Fitoterapia, 2016 - Elsevier
Two new monoterpenoid indole alkaloids, melaxillines A (1) and B (2), together with four
known alkaloids (3–6), were isolated from the roots of Melodinus axillaris. The structures …

Monoterpenoid indole alkaloids from Melodinus axillaris WT Wang exhibit anti-inflammatory activities by inhibiting the NF-κB signaling pathways

K Du, Y Liang, Z Song, C Zheng, L Lai, K Zong… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Melodinus axillaris WT Wang has been widely used as an
important medicine in China. In the folk of China, its whole plant has been used for fractures …

Melotenuines AE, cytotoxic monoterpenoid indole alkaloids from Melodinus tenuicaudatus

JW Liu, ZQ Huo, Q Zhao, XJ Hao, HP He, Y Zhang - Fitoterapia, 2019 - Elsevier
Five new monoterpenoid indole alkaloids, melotenuines AE (1–5), along with 18 known
indole alkaloids, were isolated from the twigs and leaves of Melodinus tenuicaudatus. The …

Cytotoxic indole alkaloids from Melodinus khasianus and Melodinus tenuicaudatus

W Yi, D Chen, X Ding, X Li, S Li, Y Di, Y Zhang, X Hao - Fitoterapia, 2018 - Elsevier
Four new indole alkaloids, melodinusines AD (1, 2, 6, and 7), along with 26 known indole
alkaloids, were isolated from Melodinus tenuicaudatus and Melodinus khasianus …

Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus

T Feng, Y Li, YY Wang, XH Cai, YP Liu… - Journal of natural …, 2010 - ACS Publications
Four new bisindole alkaloids, melodinines H− K (1− 4), a new monomer, melodinine L (5),
and 11 known alkaloids were isolated from Melodinus tenuicaudatus. The structures of 1− 5 …

Chemical constituents and anti-inflammatory activity of the total alkaloid extract from Melodinus cochinchinensis (Lour.) Merr. and its inhibition of the NF-κB and MAPK …

M Yang, Y Wang, Z Fan, Q Xue, GSS Njateng, Y Liu… - Phytomedicine, 2021 - Elsevier
Abstract Background Melodinus cochinchinensis (Lour.) Merr. is a medicinal plant, which is
used as a folk medicine for treating meningitis and fractures. However, the anti-inflammatory …

Melodinines A−G, Monoterpenoid Indole Alkaloids from Melodinus henryi

T Feng, XH Cai, YP Liu, Y Li, YY Wang… - Journal of natural …, 2010 - ACS Publications
Nineteen monoterpenoid indole alkaloids including seven new ones, melodinines A− G (1−
7), were isolated from Melodinus henryi. The structures of the new compounds were …

Melosuavines A–H, Cytotoxic Bisindole Alkaloid Derivatives from Melodinus suaveolens

YP Liu, YL Zhao, T Feng, GG Cheng… - Journal of Natural …, 2013 - ACS Publications
Eight new bisindole alkaloids, melosuavines A–C (1–3), having an aspidosperma-scandine
linkage, melosuavines D–F (4–6), possessing an aspidosperma-aspidosperma skeleton …