Objective: Citalopram is widely used in adolescents with major depressive disorder (MDD)
and anxiety; however, data on efficacy and safety are still limited and inconsistent. The aim …

Citalopram has by far the highest selectivity for serotonin reuptake and is used for the
treatment of depression. Therapeutic drug monitoring is clinically important for psychiatrists …

We established a method for automated quantitative analysis of (es-) citalopram and
desmethyl (es-) citalopram in serum using column-switching high performance liquid …

The burden of depression and other mental disorders is on the rise globally, and successful
treatment sometimes requires modifications of drugs and/or dose regimens. The …

A simple, rapid and robust LC method for enantiospecific separation and determination of
citalopram in drugs and pharmaceuticals was developed using UV and polarimetric …

Cytochrome (CYP) P450 enzymes have a primary role in antidepressant metabolism and
variants in these polymorphic genes are targets for pharmacogenetic investigation. This is …

Background: Double-blind clinical trials comparing citalopram with amitriptyline or other
tricyclic antidepressants are lacking in India. Aim: To evaluate the efficacy and safety of the …

Rationale S-citalopram (escitalopram) is the very active moiety of citalopram. It has been
shown in many studies to be an effective and safe antidepressant for treating major …

Citalopram is a selective serotonin (5‐HT) reuptake inhibitor (SSRI) developed by H.
Lundbeck A/S in Denmark. It is the most selective serotonin antidepressant with proven …

Column high-performance liquid chromatographic (LC) and UV spectrophotometric methods
for the quantitative determination of citalopram, a potent and selective serotonin reuptake …