Background Resveratrol is a Sirt-1-specific activator, which also exerts cardioprotective
effects that regulate redox signalling during oxidative stress and autophagy during …

Autophagic dysfunction is observed in diabetes mellitus. Resveratrol has a beneficial effect
on diabetic cardiomyopathy. Whether the resveratrol‐induced improvement in cardiac …

Recently, many studies have attempted to illustrate the mechanism of autophagy in
protection against oxidative stress to the heart induced by H2O2. However, whether …

Aims On the basis of our previous reports that cardioprotection induced by ischaemic
preconditioning induces autophagy and that resveratrol, a polyphenolic antioxidant present …

Background/Aims: Diabetic cardiomyopathy is associated with increased apoptosis and
suppressed autophagy in cardiac cells. The polyphenol resveratrol has shown beneficial …

Aged myocardium is more susceptible to ischemia/reperfusion (I/R) injury. Autophagy and
apoptosis play important roles in cardiac I/R injury. However, whether resveratrol can reduce …

Oxidative stress induced by free fatty acid aggravates endothelial injury, which leads to
diabetic cardiovascular complications. Reduction of intracellular oxidative stress may …

Resveratrol is a natural polyphenol found in various plants. It has been widely studied on
cardiovascular disorders. It is known that resveratrol can activate Sirtuin proteins and …

Loss of cardiomyocytes through apoptosis has been proposed as a cause of ventricular
remodeling and heart failure. Ischemia-and hypoxia-induced apoptosis of cardiomyocytes …

Objective Autophagy is a cellular process by which damaged components are removed.
Although autophagy can result in cell death, when optimally regulated, it might be …