Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio

GL Schwartz, AB Chapman, E Boerwinkle… - Clinical …, 2002 - academic.oup.com
Background: The value of the ratio of plasma aldosterone concentration (aldosterone) to
plasma renin activity (renin) to identify patients at risk for primary aldosteronism is …

Use of plasma aldosterone concentration-to-plasma renin activity ratio as a screening test for primary aldosteronism: a systematic review of the literature

VM Montori, WF Young - Endocrinology and Metabolism Clinics, 2002 - endo.theclinics.com
Objective. We conducted a systematic review of the literature to establish the test
characteristics (sensitivity, specificity, likelihood ratios at different cutoff values) of the …

Optimal use and interpretation of the aldosterone renin ratio to detect aldosterone excess in hypertension

S Abalkhail, MM Al-Qudhaiby, K Al-Humood… - Journal of human …, 2006 - nature.com
With the introduction of the aldosterone/renin ratio as a screening test, the detection rate of
primary aldosteronism has increased considerably. Nevertheless, no consensus has so far …

Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity

GL Schwartz, ST Turner - Clinical chemistry, 2005 - academic.oup.com
Background: The ratio of plasma aldosterone concentration to plasma renin activity (PRA) is
considered the screening test of choice for primary aldosteronism. Uncertainty exists …

Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism

P Ferrari, SG Shaw, J Nicod, E Saner… - Journal of …, 2004 - journals.lww.com
Background In recent years, the assessment of the plasma aldosterone-to-renin ratio (ARR)
has become an established screening method for the diagnosis of primary aldosteronism …

Test characteristics of the aldosterone-to-renin ratio as a screening test for primary aldosteronism

PM Jansen, BJH van den Born, WJ Frenkel… - Journal of …, 2014 - journals.lww.com
Background: The aldosterone-to-renin ratio (ARR) is a widely used screening test for
primary aldosteronism. Current guidelines recommend a cut-off value of 91 pmol/mU …

Performance of the aldosterone to renin ratio as a screening test for primary aldosteronism

A Hung, S Ahmed, A Gupta, A Davis… - The Journal of …, 2021 - academic.oup.com
Context The aldosterone to renin ratio (ARR) is the guideline-recommended screening test
for primary aldosteronism. However, there are limited data in regard to the diagnostic …

Novel approach to establishing an aldosterone: renin ratio cutoff for primary aldosteronism

AA Leung, DJ Orton, A Chin, H Sadrzadeh… - Hypertension, 2017 - Am Heart Assoc
Direct renin concentration is replacing plasma renin activity in many laboratories for the
investigation of primary aldosteronism, which may have a significant impact on the resulting …

Ratio of serum aldosterone to plasma renin concentration in essential hypertension and primary aldosteronism

S Trenkel, C Seifarth, H Schobel… - Experimental and …, 2002 - thieme-connect.com
The ratio of serum aldosterone to plasma renin activity (PRA) has been proposed as
sensitive screening method in the diagnosis of primary aldosteronism under random …

A useful tool to improve the case detection rate of primary aldosteronism: the aldosterone–renin ratio (ARR)-App

GP Rossi, V Bisogni - Journal of Hypertension, 2016 - journals.lww.com
The aldosterone–renin ratio is the most popular test for the case detection of primary
aldosteronism, which entails the most common, albeit overlooked, form of endocrine …