Effect of initial fluid resuscitation on subsequent treatment in uncontrolled hemorrhagic shock in rats

X Nan, W Xi-Chun, D You-Fang, L Ren, T Kun-Lun - Shock, 2004 - journals.lww.com
Using a modified uncontrolled hemorrhage shock model with massive splenic and vascular
injury, we evaluated outcome and tissue oxidation injury with different resuscitation …

The effect of vigorous fluid resuscitation in uncontrolled hemorrhagic shock after massive splenic injury

E Solomonov, M Hirsh, A Yahiya… - Critical care …, 2000 - journals.lww.com
Objective: Using a standardized massive splenic injury model of uncontrolled hemorrhagic
shock, we studied the effect of vigorous fluid resuscitation on the hemodynamic response …

Fluid resuscitation in a model of uncontrolled hemorrhage: too much too early, or too little too late?

A Leppäniemi, R Soltero, D Burris, E Pikoulis… - Journal of Surgical …, 1996 - Elsevier
Early fluid resuscitation in hypotensive trauma patients is controversial due to the risk of
increasing blood loss and mortality. We determined the effects of infusion rate and time of …

A novel fluid resuscitation therapy for hemorrhagic shock

JW Roy, MC Graham, AM Griffin, JL Gainer - Shock, 1998 - journals.lww.com
Fluid resuscitation is the usual therapy for hemorrhagic shock, and frequently consists of the
infusion of large volumes of electrolyte solutions. However, to be successful, this therapy …

Continuous fluid resuscitation and splenectomy for treatment of uncontrolled hemorrhagic shock after massive splenic injury

OA Hatoum, Y Bashenko, M Hirsh… - Journal of Trauma and …, 2002 - journals.lww.com
Background Using a standardized massive splenic injury (MSI) model of uncontrolled
hemorrhagic shock, we studied the effect of continuous fluid resuscitation and splenectomy …

Small-volume fluid resuscitation with hypertonic saline prevents inflammation but not mortality in a rat model of hemorrhagic shock

S Bahrami, K Zimmermann, Z Szelényi, J Hamar… - Shock, 2006 - journals.lww.com
Hemorrhage remains a primary cause of death in civilian and military trauma. Permissive
hypotensive resuscitation is a possible approach to reduce bleeding in patients until they …

Experimental study of controlled fluid resuscitation in the treatment of severe and uncontrolled hemorrhagic shock

YQ Lu, XJ Cai, LH Gu, Q Wang… - Journal of Trauma and …, 2007 - journals.lww.com
Background: Hemorrhagic shock is a common clinic emergency case. The fluid resuscitation
method in the presurgical care of hypotensive trauma patients is open to debate. This study …

Controlled resuscitation for uncontrolled hemorrhagic shock

D Burris, P Rhee, C Kaufmann, E Pikoulis… - Journal of Trauma …, 1999 - journals.lww.com
Objective To test the hypothesis that controlled resuscitation can lead to improved survival in
otherwise fatal uncontrolled hemorrhage. Methods Uncontrolled hemorrhage was induced …

Uncontrolled hemorrhagic shock outcome model in rats

A Capone, P Safar, SW Stezoski, A Peitzman… - Resuscitation, 1995 - Elsevier
During uncontrolled hemorrhagic shock (UHS) in acute animal models, attempts to achieve
normotension with iv fluid resuscitation (FR) caused further bleeding and higher acute …

Hemodilution as a result of aggressive fluid resuscitation aggravates coagulopathy in a rat model of uncontrolled hemorrhagic shock

K Nishi, A Takasu, H Shinozaki… - Journal of Trauma …, 2013 - journals.lww.com
BACKGROUND The relationship between dilution caused by fluid resuscitation and blood
coagulability during ongoing, uncontrolled hemorrhagic shock (UHS) remains unclear. We …