Pregnancy-associated malaria is a major health problem, which mainly affects primigravidae
living in malaria endemic areas. The syndrome is precipitated by accumulation of infected …

Malaria is a major global health problem. Pregnant women are susceptible to infection
regardless of previously acquired immunity. Placental malaria is caused by parasites …

Background Protection against pregnancy associated malaria (PAM) is associated with high
levels of anti-VAR2CSA antibodies. This protection is obtained by the parity dependent …

Background In Plasmodium falciparum malaria endemic areas placental malaria (PM) is an
important complication of malaria. The recurrence of malaria in primigravidae women …

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family mediates
parasite sequestration in small capillaries through tissue-specific cytoadherence. The best …

Plasmodium falciparum parasites that bind to chondroitin sulphate A (CSA) express unique
variant surface antigens that are involved in the placental sequestration that precipitates …

Pregnancy-associated malaria (PAM) is associated with the massive sequestration of
erythrocytes infected with CSA-binding parasites in the placenta. Natural protective immunity …

Introduction: Several malaria vaccines are under various phases of development with some
promising results. In placental malaria (PM) a deliberately anti-disease approach is …

Different domains of a novel full-length var gene (termed 732 var) isolated from a placenta of
a malaria-infected woman were expressed in Escherichia coli as recombinant proteins and …

In Plasmodium falciparum, var genes encode adhesive proteins that are transported to the
surface of infected erythrocytes and act as major virulence determinants for infected …