Identification of a major dimorphic region in the functionally critical N-terminal ID1 domain of VAR2CSA
The VAR2CSA protein of Plasmodium falciparum is transported to and expressed on the
infected erythrocyte surface where it plays a key role in placental malaria (PM). It is the …
infected erythrocyte surface where it plays a key role in placental malaria (PM). It is the …
Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 …
M Resende, SB Ditlev, MA Nielsen, S Bodevin… - International journal for …, 2009 - Elsevier
Individuals living in areas with high Plasmodium falciparum transmission acquire immunity
to malaria over time and adults have a markedly reduced risk of contracting severe disease …
to malaria over time and adults have a markedly reduced risk of contracting severe disease …
Transcribed var Genes Associated with Placental Malaria in MalawianWomen
MF Duffy, A Caragounis, R Noviyanti… - Infection and …, 2006 - Am Soc Microbiol
Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-
infected erythrocytes isolated from placentas is important for attempts to develop a …
infected erythrocytes isolated from placentas is important for attempts to develop a …
[HTML][HTML] Comparison of functional assays used in the clinical development of a placental malaria vaccine
C Pehrson, KK Heno, Y Adams, M Resende… - Vaccine, 2017 - Elsevier
Background Malaria in pregnancy is associated with significant morbidity in pregnant
women and their offspring. Plasmodium falciparum infected erythrocytes (IE) express …
women and their offspring. Plasmodium falciparum infected erythrocytes (IE) express …
Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: A receptor for human placental infection
Malaria during the first pregnancy causes a high rate of fetal and neonatal death. The
decreasing susceptibility during subsequent pregnancies correlates with acquisition of …
decreasing susceptibility during subsequent pregnancies correlates with acquisition of …
Identification of a 67‐amino‐acid region of the Plasmodium falciparum variant surface antigen that binds chondroitin sulphate A and elicits antibodies reactive with …
The complications of malaria in pregnancy are caused by the massive sequestration of
parasitized erythrocytes (PE) in the placenta. Placental isolates of Plasmodium falciparum …
parasitized erythrocytes (PE) in the placenta. Placental isolates of Plasmodium falciparum …
Structural and immunological correlations between the variable blocks of the VAR2CSA domain DBL6ε from two Plasmodium falciparum parasite lines
S Gangnard, C Badaut, S Ramboarina, B Baron… - Journal of molecular …, 2013 - Elsevier
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), a family of adhesins of
the falciparum species of the malaria parasite, is exposed on the surface of the infected …
the falciparum species of the malaria parasite, is exposed on the surface of the infected …
Prospects and Pitfalls of Pregnancy‐Associated Malaria Vaccination Based on the Natural Immune Response to Plasmodium falciparum VAR2CSA‐Expressing …
EG Kane, AW Taylor-Robinson - Malaria Research and …, 2011 - Wiley Online Library
Pregnancy‐associated malaria, a manifestation of severe malaria, is the cause of up to
200,000 infant deaths a year, through the effects of placental insufficiency leading to growth …
200,000 infant deaths a year, through the effects of placental insufficiency leading to growth …
Multiplexing detection of IgG against Plasmodium falciparum pregnancy-specific antigens
Background Pregnant women exposed to Plasmodium falciparum generate antibodies
against VAR2CSA, the parasite protein that mediates adhesion of infected erythrocytes to …
against VAR2CSA, the parasite protein that mediates adhesion of infected erythrocytes to …
Functional and immunological characterization of the var2CSA-DBL5ɛ domain of a placental Plasmodium falciparum isolate
S Gangnard, NGT Ndam, S Gnidehou… - Molecular and …, 2010 - Elsevier
Pregnancy-associated malaria (PAM) arises from sequestration of Plasmodium falciparum-
parasitized erythrocytes (PE) in the placenta, leading to chronic symptoms in the expectant …
parasitized erythrocytes (PE) in the placenta, leading to chronic symptoms in the expectant …