Signals of energy homeostasis interact closely with neural circuits of motivation to control
food intake. An emerging hypothesis is that the transition to maladaptive feeding behavior …

The overconsumption of highly caloric and palatable foods has caused a surge in obesity
rates in the past half century, thereby posing a healthcare challenge due to the array of …

During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

With the bleak outlook that 75% of Americans will be overweight or obese in 10 years, it is
essential to find efficient help very soon. Knowledge of the powerful and complex neural …

The traditional view of neural regulation of body energy homeostasis focuses on internal
feedback signals integrated in the hypothalamus and brainstem and in turn leading to …

With the still‐growing prevalence of obesity worldwide, major efforts are made to understand
the various behavioral, environmental, and genetic factors that promote excess fat gain …

The neural control of appetite is important for understanding motivated behavior as well as
the present rising prevalence of obesity. Over the past several years, new tools for cell type …

Objectives: This chapter reviews brain imaging findings in anorexia and bulimia nervosa
which characterize brain circuitry that may contribute to the pathophysiology of eating …

Interest in the control of feeding has increased as a result of the obesity epidemic and rising
incidence of metabolic diseases. The brain detects alterations in energy stores and triggers …

Food intake and energy expenditure are determinants of metabolic phenotype and are
regulated by the CNS. Although humans have a well-balanced homeostatic feedback loop …