Differential expression of the Duffy antigen receptor for chemokines according to RBC age and FY genotype

IJ Woolley, KA Hotmire, RM Sramkoski… - …, 2000 - Wiley Online Library
BACKGROUND: The Duffy (Fy) blood group (also known as Duffy antigen receptor for
chemokines, or DARC) may be involved in regulation of the level of circulating …

Duffy blood group and malaria

DM Langhi, J Orlando Bordin - Hematology, 2006 - Taylor & Francis
Very important progress has been made over the last years in understanding the Duffy blood
group system and its complexity. The Duffy blood group antigen serves not only as blood …

A clinically applicable method for determining the three major alleles at the Duffy (FY) blood group locus using polymerase chain reaction with allele‐specific primers

ML Olsson, C Hansson, ND Avent, IE Akesson… - …, 1998 - Wiley Online Library
BACKGROUND: The clinically significant antigens of the Duffy (Fy [FY]) blood group system
are expressed on the red cell form of the FY glycoprotein, a promiscuous chemokine …

[引用][C] The Duffy blood group antigen: an update

K Wasniowska, TJ Hadley - Transfusion medicine reviews, 1994 - Elsevier
SIGNIFICANT progress has been made in our understanding of the Duffy blood group
antigen over the past several years. It is now known that this antigen displays the …

From malaria to chemokine receptor: the emerging physiologic role of the Duffy blood group antigen

TJ Hadley, SC Peiper - Blood, The Journal of the American …, 1997 - ashpublications.org
O phenotype and denoted as Fy (a0b0). When Duffy-negative individuals of African descent
develop anti-Duffy alloanti-NE OF THE MOST notable achievements of biomedical research …

Molecular basis and structure-activity relationships of the Duffy blood group antigens: chemokine and Plasmodium vivax receptors

C Tournamille - Transfusion Clinique et Biologique: Journal de la …, 2000 - europepmc.org
Duffy blood group antigens are of major interest in clinical medicine as they are not only
involved in blood transfusion risks and occasionally in neonatal hemolytic disease, but also …

Microsatellite variation and evolution of the human Duffy blood group polymorphism

S Seixas, N Ferrand, J Rocha - Molecular biology and evolution, 2002 - academic.oup.com
The human Duffy blood group (FY) antigens are transmembrane glycoproteins that function
as receptors for chemokines and for the malarial parasite Plasmodium vivax (reviewed in …

The role of the human Duffy antigen receptor for chemokines in malaria susceptibility: current opinions and future treatment prospects

FB Ntumngia, R Thomson-Luque, CV Pires… - Journal of receptor …, 2016 - Taylor & Francis
The Duffy antigen receptor for chemokine (DARC) is a nonspecific receptor for several
proinflammatory cytokines. It is homologous to the G-protein chemokine receptor …

The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation

JS Lee, MM Wurfel, G Matute-Bello… - The Journal of …, 2006 - journals.aai.org
Abstract The Duffy blood group Ag (dfy) binds selective CXC and CC chemokines at high
affinity and is expressed on erythrocytes and endothelial cells. However, it does not transmit …

Arg89Cys Substitution Results in Very Low Membrane Expression of the Duffy Antigen/Receptor for Chemokines in Fyx Individuals

C Tournamille, C Le Van Kim, P Gane… - Blood, The Journal …, 1998 - ashpublications.org
The Duffy (FY) blood group antigens are carried by the DARC glycoprotein, a widely
expressed chemokine receptor. The molecular basis of the Fya/Fyb and Fy (ab-) …