Role of inflammatory cytokines in genesis and treatment of atherosclerosis

E Biros, JE Reznik, CS Moran - Trends in cardiovascular medicine, 2022 - Elsevier
Atherosclerosis demonstrates an increased rate of vascular smooth muscle cells (VSMC)
plasticity characterized by switching from the differentiated contractile phenotype to a de …

[HTML][HTML] Inflammatory cytokines and atherosclerotic plaque progression. Therapeutic implications

AV Sterpetti - Current Atherosclerosis Reports, 2020 - Springer
Abstract Purpose of the Review Inflammatory cytokines play a major role in atherosclerotic
plaque progression. This review summarizes the rationale for personalized anti …

Cytokines in atherosclerosis: pathogenic and regulatory pathways

A Tedgui, Z Mallat - Physiological reviews, 2006 - journals.physiology.org
Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
The notion of atherosclerosis as a chronic inflammatory disease has intensified research on
the role of cytokines and the way these molecules act and interact to initiate and sustain …

[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

Pro‐and anti‐inflammatory cytokine networks in atherosclerosis

MV Autieri - International Scholarly Research Notices, 2012 - Wiley Online Library
Despite advances in prevention and treatment, atherosclerotic vascular disease continues to
account for significant morbidity, mortality, and economic burden in the western world. Our …

Key roles of inflammation in atherosclerosis: Mediators involved in orchestrating the inflammatory response and its resolution in the disease along with therapeutic …

YH Chan, DP Ramji - Atherosclerosis: Methods and Protocols, 2022 - Springer
Inflammation is a critical driver of all stages of atherosclerosis, from lesion development to
plaque rupture. Cytokines are mediators of the immune response and in atherosclerosis, the …

Inflammatory cytokines and cardiovascular disease

T Ito, U Ikeda - Current Drug Targets-Inflammation & Allergy, 2003 - ingentaconnect.com
The designation of atherosclerosis as a chronic inflammatory process represents an
interesting paradigmatic shift for cardiologists. The plasma concentrations of interleukin-6 …

Recent advances on the role of cytokines in atherosclerosis

H Ait-Oufella, S Taleb, Z Mallat… - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease of the arterial wall driven by innate and
adaptive immune responses. Inflammation controls the development and the destabilization …

Inflammation and immune responses in atherosclerosis

DR Greaves, KM Channon - Trends in immunology, 2002 - cell.com
Recent studies have highlighted the role of inflammatory mediators and the cells of the
innate and adaptive immune response in the initiation, growth and rupture of atherosclerotic …