Background/objectives The aim of the current study was to investigate the inhibitory effect of
lycopene (LYC), a major carotenoid present in tomato, on high-fat and high-fructose western …

Obesity, which is caused by an energy imbalance between calorie intake and consumption,
has become a major international health burden. Obesity increases the risk of insulin …

Systemic inflammation is an important determinant of synaptic dysfunction, but the
underlying molecular mechanisms remain elusive. Lycopene (LYC), a major carotenoid …

A Western diet, high in saturated fats, has been linked to the development of cognitive
impairment. Lycopene has recently received considerable attention for its potent protective …

The incidence of neurodegenerative diseases is severely increasing with ageing. Lycopene
(LYC), a carotenoid pigment, has been reported to have antioxidant, anti-inflammatory and …

This passive overconsumption of western diet has precipitated a steep rise in obesity and its
comorbidities, and obesity has become one of the main threats to health worldwide. Thus …

Sea-buckthorn flavonoids (SFs) have been used as functional food components for their
bioactive potential in preventing metabolic complications caused by diet, such as obesity …

A high-fat (HF) diet is a major predisposing factor of neuroinflammation and cognitive
deficits. Recently, changes in the gut microbiota have been associated with …

Hippocampal insulin resistance is the key factor in cognitive deficits. The obesity induces
chronic inflammation and the inflammation molecules suppressors of cytokine signaling3 …

Background Quercetin (QUE) is a flavonol reported with anti-inflammatory and antioxidant
activities, and previous results from the group of this study have demonstrated its …