Seven patients were included in this study, all of whom were men with atherosclerotic
occlusion. The mean age was 65· 3 years (SD 8· 0; range 60–74), and the mean bodyweight …

Background Preclinical studies have established that implantation of bone marrow-
mononuclear cells, including endothelial progenitor cells, into ischaemic limbs increases …

Mesenchymal stromal cells (MSCs) have the potential to treat many myocardial diseases.
We investigated whether these multipotent stem cells derived from bone marrow could be …

1 Korbling M, Estrov Z. Adult stem cells for tissue repair—new therapeutic concept? N Engl J
Med 2003; 349: 570–82. 2 Tateishi-Yuyama E, Matsubara H, Murohara T, et al. Therapeutic …

Critical leg ischemia is associated with a high risk of amputation when revascularization is
not possible. Cell therapy based on bone marrow-derived mononuclear cells or with …

Sir—Emma Lagaaij and colleagues (Jan 6, p 37) 1 report that after renal transplantation a
substantial proportion of the vascular endothelial cells within the graft were of recipient …

Background Vascular endothelial cells lost from the bloodvessel endothelium through
necrosis or apoptosis must be replaced. We investigated in a leukaemia model whether …

Background. In 2003 we started investigations concerning the possibility of using new
techniques, including bone-marrow cell implantation, in the therapy of critical leg ischaemia …

With many patients in desperate need of improved cardiac function, the idea to use adult
stem cells for solid-organ repair is attractive. 1 In 2002, Strauer and co-workers described a …

1 Kang HJ, Kim HS, Zhang SY, et al. Effects of intracoronary infusion of peripheral blood
stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic …