Granulation tissue formation is an example of new tissue development in an adult. Its rich
vascular network has been thought to derive via angiogenic sprouting and extension of …

Background: Coronary endothelial dysfunction (CED) causes angina/ischemia in patients
with nonobstructive coronary artery disease (NOCAD). Patients with CED have decreased …

Current stem cell protocols for ischemic heart disease are limited by the small numbers of
cells that can be obtained by bone marrow aspirate. To increase myocardial delivery of bone …

Objective: A subset of adult peripheral blood leukocytes functions as endothelial progenitor
cells that incorporate into the vasculature in animal models of neovascularization. The basic …

BACKGROUND: We hypothesized that granulocyte macrophage colony-stimulating factor
(GM-CSF) administration will be safe and will improve endothelial dysfunction and exercise …

We are writing in regard to your published article “Isolation of endothelial cells and their
progenitor cells from human peripheral blood”(J Vasc Surg 2000; 31: 181-9). We read with …

Bone marrow-derived CD34+ cells are a well-characterized population of stem cells that
have traditionally been used clinically to reconstitute the hematopoietic system after …

Aims Previous trials that investigated cell therapy as an adjunctive therapy after acute
myocardial infarction (AMI) have shown conflicting results. We designed a randomized …

METHODS Thirty four patients (mean (SEM) age 62.5 (1.7) years) with angiographically
documented stable CAD, and 36 healthy control subjects (mean (SEM) age 53.6 (2.0) years) …

The level of circulating stromal progenitor cells carrying osteonectin (ON), a marker of
osteogenic differentiation, was evaluated by flow cytometry in blood of patients with coronary …