Analysis of PLA2R1 and HLA-DQA1 sequence variants in Japanese patients with idiopathic and secondary membranous nephropathy
H Kaga, A Komatsuda, A Omokawa, S Okuyama… - Clinical and …, 2018 - Springer
Background Several recent studies in patients with idiopathic membranous nephropathy
(iMN) from Western and Asian counties showed that some single nucleotide polymorphisms …
(iMN) from Western and Asian counties showed that some single nucleotide polymorphisms …
[HTML][HTML] Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy
KZ Latt, K Honda, M Thiri, Y Hitomi, Y Omae, H Sawai… - Scientific reports, 2018 - nature.com
The associations of single nucleotide polymorphisms (SNPs) in PLA2R1 and HLA-DQA1, as
well as HLA-DRB1* 15: 01-DQB1* 06: 02 haplotype with idiopathic membranous …
well as HLA-DRB1* 15: 01-DQB1* 06: 02 haplotype with idiopathic membranous …
PLA2R antibodies, glomerular PLA2R deposits and variations in PLA2R1 and HLA-DQA1 genes in primary membranous nephropathy in South Asians
Background Antibodies to M-type phospholipase A2 receptor (PLA2R) correlate with clinical
activity of primary membranous nephropathy (PMN). Risk alleles in PLA2R1 and HLA-DQA1 …
activity of primary membranous nephropathy (PMN). Risk alleles in PLA2R1 and HLA-DQA1 …
[HTML][HTML] High-density Association Mapping and Interaction Analysis of PLA2R1 and HLA Regions with Idiopathic Membranous Nephropathy in Japanese
M Thiri, K Honda, K Kashiwase, A Mabuchi, H Suzuki… - Scientific reports, 2016 - nature.com
Although recent studies showed anti-PLA2R antibody plays a crucial role in idiopathic
membranous nephropathy (IMN), detailed HLA mapping and interaction between the HLA …
membranous nephropathy (IMN), detailed HLA mapping and interaction between the HLA …
Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies
P Sekula, Y Li, HC Stanescu, M Wuttke… - Nephrology Dialysis …, 2017 - academic.oup.com
Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in
adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants …
adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants …
Association of SNPs in PLA2R1 with idiopathic and secondary membranous nephropathy in two Chinese cohorts
CX Tian, L Li, P Qiu, YR Qiu - British Journal of Biomedical Science, 2020 - Taylor & Francis
Objectives: Specific single-nucleotide polymorphisms (SNPs) in the M-type phospholipase
A2 receptor-1 (PLA2R1) are associated with increased risk of idiopathic membranous …
A2 receptor-1 (PLA2R1) are associated with increased risk of idiopathic membranous …
Risk HLA-DQA1 and PLA2R1 Alleles in Idiopathic Membranous Nephropathy
HC Stanescu, M Arcos-Burgos, A Medlar… - … England Journal of …, 2011 - Mass Medical Soc
Background Idiopathic membranous nephropathy is a major cause of the nephrotic
syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic …
syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic …
Association of 10 Polymorphisms in PLA2R1 and HLA DQA1 Genes with Primary Membranous Nephropathy Risk: A Meta-Analysis and a Meta-Regression
T Dhaouadi, A Riahi, TB Abdallah… - Biomarker …, 2024 - journals.sagepub.com
Background: Although, several studies have assessed the association of the phospholipase
A2 receptor (PLA2R) and HLA-DQA1 SNPs with primary membranous nephropathy (PMN) …
A2 receptor (PLA2R) and HLA-DQA1 SNPs with primary membranous nephropathy (PMN) …
HLA-DRB1* 15: 01 and HLA-DRB3* 02: 02 in PLA2R-related membranous nephropathy
Idiopathic membranous nephropathy (MN) is associated with HLA; however, the HLA allele
involved remains unknown. To identify the HLA risk alleles associated with phospholipase …
involved remains unknown. To identify the HLA risk alleles associated with phospholipase …
Genetic variants in membranous nephropathy: perhaps a perfect storm rather than a straightforward conformeropathy?
DJ Salant - Journal of the American Society of Nephrology, 2013 - journals.lww.com
Primary (or idiopathic) membranous nephropathy is an organ-specific autoimmune disease
in which circulating antibodies to a conformation-dependent epitope in the target antigen …
in which circulating antibodies to a conformation-dependent epitope in the target antigen …
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