Since the publication of the Surviving Sepsis Campaign guidelines, a number of additional
and highly relevant studies have been published addressing the issue of vasopressor use …

Background Vasopressors are commonly applied to restore and maintain blood pressure in
patients with sepsis. We aimed to evaluate the current practice and therapeutic goals …

Septic shock is the most serious complication of sepsis and requires emergent recognition
and treatment. Considerable efforts have been made to evaluate different therapies for …

Septic shock is mainly characterized—in addition to hypovolemia—by vasoplegia as a
consequence of a release of inflammatory mediators. Systemic vasodilatation due to …

Methods: We selected studies in adults with septic shock that compared the outcomes of
patients treated with vasopressin versus norepinephrine. Cochrane ROB 2.0 and the …

Septic shock is associated with a relative deficiency of the endogenous stress hormone
vasopressin. In shock states vasopressin binds to vasopressin receptors on vascular smooth …

The use of norepinephrine or epinephrine can be left to the discretion of the treating
physician. Low-dose vasopressin administration remains an option for catecholamine …

The definition of septic shock includes sepsis-induced hypotension despite adequate fluid
resuscitation, along with the presence of organ perfusion abnormalities, and ultimately cell …

Objective: To evaluate the effects of two arginine vasopressin (AVP) dose regimens (0.033
vs. 0.067 IU/min) on treatment efficacy, hemodynamic response, prevalence of adverse …

Septic shock is a medical emergency that is associated with mortality rates of 40–70%.
Prompt recognition and institution of effective therapy is required for optimal outcome. When …