Static and dynamic 18F–FET PET for the characterization of gliomas defined by IDH and 1p/19q status

A Verger, G Stoffels, EK Bauer, P Lohmann… - European journal of …, 2018 - Springer
Purpose The molecular features isocitrate dehydrogenase (IDH) mutation and 1p/19q co-
deletion have gained major importance for both glioma typing and prognosis and have …

Static 18F-FET PET and DSC-PWI based on hybrid PET/MR for the prediction of gliomas defined by IDH and 1p/19q status

S Song, L Wang, H Yang, Y Shan, Y Cheng, L Xu… - European …, 2021 - Springer
Objectives To investigate the predictive value of static O-(2-18 F-fluoroethyl)-L-tyrosine
positron emission tomography (18 F-FET PET) and cerebral blood volume (CBV) for glioma …

Integration of dynamic parameters in the analysis of 18F-FDopa PET imaging improves the prediction of molecular features of gliomas

M Ginet, T Zaragori, PY Marie, V Roch… - European journal of …, 2020 - Springer
Abstract Purpose 18 F-FDopa PET imaging of gliomas is routinely interpreted with
standardized uptake value (SUV)-derived indices. This study aimed to determine the added …

Identification of time-to-peak on dynamic 18F-FET-PET as a prognostic marker specifically in IDH1/2 mutant diffuse astrocytoma

B Suchorska, A Giese, A Biczok, M Unterrainer… - Neuro …, 2018 - academic.oup.com
Background Stratification of glioma according to isocitrate dehydrogenase 1/2 (IDH1/2)
mutation and 1p/19q codeletion status has gained major importance in the new World …

Biological tumour volumes of gliomas in early and standard 20–40 min 18F-FET PET images differ according to IDH mutation status

M Unterrainer, I Winkelmann, B Suchorska… - European journal of …, 2018 - Springer
Purpose For the clinical evaluation of O-(2-18 F-fluoroethyl)-l-tyrosine (18 F-FET) PET
images, the use of standard summation images obtained 20–40 min after injection is …

Non-invasive prediction of IDH-wildtype genotype in gliomas using dynamic 18F-FET PET

F Vettermann, B Suchorska, M Unterrainer… - European journal of …, 2019 - Springer
Purpose According to the updated WHO classification of gliomas with its emphasis on
molecular parameters, tumours with an IDH-wildtype status have a dismal prognosis. To …

18F-DOPA uptake does not correlate with IDH mutation status and 1p/19q co-deletion in glioma

F Cicone, L Carideo, C Scaringi, A Arcella… - Annals of nuclear …, 2019 - Springer
Objective The role of amino acid positron emission tomography (PET) in glioma grading and
outcome prognostication has not yet been well established. This is particularly true in the …

[HTML][HTML] Prediction of survival in patients with IDH-wildtype astrocytic gliomas using dynamic O-(2-[18F]-fluoroethyl)-l-tyrosine PET

EK Bauer, G Stoffels, T Blau, G Reifenberger… - European journal of …, 2020 - Springer
Purpose Integrated histomolecular diagnostics of gliomas according to the World Health
Organization (WHO) classification of 2016 has refined diagnostic accuracy and prediction of …

[HTML][HTML] The value of FET PET/CT in recurrent glioma with a different IDH mutation status: the relationship between imaging and molecular biomarkers

M Skoblar Vidmar, A Doma, U Smrdel, K Zevnik… - International Journal of …, 2022 - mdpi.com
The evaluation of treatment response remains a challenge in glioma cases because the
neuro oncological therapy can lead to the development of treatment-related changes (TRC) …

IDH mutation is paradoxically associated with higher 18F-FDOPA PET uptake in diffuse grade II and grade III gliomas

A Verger, P Metellus, Q Sala, C Colin, E Bialecki… - European journal of …, 2017 - Springer
Abstract Purpose The World Health Organization Classification of Tumors of the Central
Nervous System has recently been updated by the integration of diagnostic and prognostic …