Malaria remains one of the world's most prevalent tropical diseases because of its high
mortality and morbidity burden, as well as its economic and social impacts on the …

Human malaria infection begins with a one-time asymptomatic liver stage followed by a
cyclic symptomatic blood stage. All high-throughput malaria drug discovery efforts have …

Despite substantial scientific progress over the past two decades, malaria remains a
worldwide burden that causes hundreds of thousands of deaths every year. New, affordable …

This digest covers some of the most relevant progress in malaria drug discovery published
between 2010 and 2012. There is an urgent need to develop new antimalarial drugs. Such …

Background Humans have suffered from the burden of malarial infections for thousands of
years, and the disease has greatly influenced human evolution and history [1]–[3]. Malaria …

Efforts to develop an effective malaria vaccine are yet to be successful and thus
chemotherapy remains the mainstay of malaria control strategy. Plasmodium falciparum, the …

Over time, several exciting advances have been made in the treatment and prevention of
malaria; however, this devastating disease continues to be a major global health problem …

Malaria remains a global public health threat, with half of the world's population at risk.
Despite numerous efforts in the past decade to develop new antimalarial drugs to surmount …

Terminal and benign diseases alike in adults, children, pregnant women, and others are
successfully treated by pharmacological inhibitors that target human enzymes. Despite …

Most malaria drug development focuses on parasite stages detected in red blood cells, even
though, to achieve eradication, next-generation drugs active against both erythrocytic and …