[HTML][HTML] Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host

ST Sonnleitner, M Prelog, S Sonnleitner… - Nature …, 2022 - nature.com
Different scenarios explaining the emergence of novel variants of concern (VOC) of the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported …

Recurrent SARS-CoV-2 mutations in immunodeficient patients

SAJ Wilkinson, A Richter, A Casey, H Osman… - Virus …, 2022 - academic.oup.com
Long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in
immunodeficient patients are an important source of variation for the virus but are …

[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature Reviews …, 2021 - nature.com
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …

Emergence of multiple SARS-CoV-2 antibody escape variants in an immunocompromised host undergoing convalescent plasma treatment

L Chen, MC Zody, C Di Germanio, R Martinelli… - Msphere, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern
(VOCs), harboring spike protein N-terminal domain (NTD) or receptor-binding domain (RBD) …

SARS-CoV-2 within-host diversity and transmission

KA Lythgoe, M Hall, L Ferretti, M de Cesare… - Science, 2021 - science.org
INTRODUCTION Genome sequencing at an unprecedented scale during the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is helping to track spread of …

[HTML][HTML] Evolutionary trajectory of SARS-CoV-2 and emerging variants

J Singh, P Pandit, AG McArthur, A Banerjee… - Virology journal, 2021 - Springer
The emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), and more recently, the independent evolution of multiple SARS-CoV-2 …

[HTML][HTML] Emerging SARS-CoV-2 variants: genetic variability and clinical implications

A Dubey, S Choudhary, P Kumar, S Tomar - Current microbiology, 2022 - Springer
The sudden rise in COVID-19 cases in 2020 and the incessant emergence of fast-spreading
variants have created an alarming situation worldwide. Besides the continuous …

[HTML][HTML] Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants

S Weigang, J Fuchs, G Zimmer, D Schnepf… - Nature …, 2021 - nature.com
The origin of SARS-CoV-2 variants of concern remains unclear. Here, we test whether intra-
host virus evolution during persistent infections could be a contributing factor by …

Long-term evolution of SARS-CoV-2 in an immunocompromised patient with non-Hodgkin lymphoma

V Borges, J Isidro, M Cunha, D Cochicho, L Martins… - Msphere, 2021 - Am Soc Microbiol
Recent studies have shown that persistent SARS-CoV-2 infections in immunocompromised
patients can trigger the accumulation of an unusual high number of mutations with potential …

[HTML][HTML] No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2

L van Dorp, D Richard, CCS Tan, LP Shaw… - Nature …, 2020 - nature.com
COVID-19 is caused by the coronavirus SARS-CoV-2, which jumped into the human
population in late 2019 from a currently uncharacterised animal reservoir. Due to this recent …