Lung transplant recipients with idiopathic pulmonary fibrosis have impaired alloreactive immune responses

P Wang, J Leung, A Lam, S Lee, DR Calabrese… - The Journal of Heart and …, 2022 - Elsevier
Background Telomere dysfunction is associated with idiopathic pulmonary fibrosis (IPF) and
worse outcomes following lung transplantation. Telomere dysfunction may impair immunity …

[HTML][HTML] Impact of age and telomere length on circulating T cells and rejection risk after lung transplantation for idiopathic pulmonary fibrosis

ME Snyder, MR Anderson, LJ Benvenuto… - The Journal of Heart and …, 2023 - Elsevier
Background Most idiopathic pulmonary fibrosis (IPF) lung transplant recipients (IPF-LTRs)
have short telomere (ST) length. Inherited mutations in telomere-related genes are …

Telomere length in patients with pulmonary fibrosis associated with chronic lung allograft dysfunction and post–lung transplantation survival

CA Newton, J Kozlitina, JR Lines, V Kaza… - The Journal of Heart and …, 2017 - Elsevier
Background Prior studies have shown that patients with pulmonary fibrosis with mutations in
the telomerase genes have a high rate of certain complications after lung transplantation …

Lung transplant recipients with telomere-mediated pulmonary fibrosis have increased risk for hematologic complications

SJ Hannan, CJ Iasella, RM Sutton, ID Popescu… - American Journal of …, 2023 - Elsevier
Idiopathic pulmonary fibrosis lung transplant recipients (IPF-LTRs) are enriched for short
telomere length (TL) and telomere gene rare variants. A subset of patients with …

Association of donor and recipient telomere length with clinical outcomes following lung transplantation

AM Courtwright, S Fried, JA Villalba, A Moniodis… - PLoS …, 2016 - journals.plos.org
Background Patients with short telomere syndromes and pulmonary fibrosis have increased
complications after lung transplant. However, the more general impact of donor and …

[HTML][HTML] Lung transplantation for idiopathic pulmonary fibrosis enriches for individuals with telomere-mediated disease

JK Alder, RM Sutton, CJ Iasella, M Nouraie… - The Journal of Heart and …, 2022 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is the most common indication for lung
transplantation in North America and variants in telomere-maintenance genes are the most …

Running short on time: lung transplant evaluation for telomere-related pulmonary fibrosis

CK Garcia - Chest, 2015 - journal.chestnet.org
Idiopathic pulmonary fibrosis (IPF) is the most common subtype of interstitial lung disease
(ILD) and disproportionately affects older adults. 1 The pathogenesis of IPF in some patients …

Impaired cytomegalovirus immunity in idiopathic pulmonary fibrosis lung transplant recipients with short telomeres

I Popescu, H Mannem, SA Winters, A Hoji… - American journal of …, 2019 - atsjournals.org
Rationale: Cytomegalovirus (CMV)-related morbidities remain one of the most common
complications after lung transplantation and have been linked to allograft dysfunction, but …

[HTML][HTML] Short airway telomeres are associated with primary graft dysfunction and chronic lung allograft dysfunction

JR Greenland, R Guo, S Lee, L Tran, B Kapse… - The Journal of Heart and …, 2023 - Elsevier
Primary graft dysfunction (PGD) is a major risk factor for chronic lung allograft dysfunction
(CLAD) following lung transplantation, but the mechanisms linking these pathologies are …

Airway complications in lung transplant recipients with telomere‐related interstitial lung disease

B Choi, J Messika, A Courtwright… - Clinical …, 2022 - Wiley Online Library
Introduction Patients with short telomere‐related interstitial lung disease (ILD) have worse
outcomes after lung transplantation. We hypothesized that post‐transplant airway …