Why Preclinical Imaging and What Will Happen in the Future?

R Solgi, PE Sharif - Frontiers in Biomedical Technologies, 2021 - scholar.archive.org
Small laboratory animals such as mice are being used to understand more about the biology
of human system. This would create a setup where more information is extracted from …

[PDF][PDF] In vivo preclinical imaging

J Comley - Drug Discovery, 2011 - ddw-online.com
In vivo imaging is increasingly deployed across the drug development process, with
applicability in target identification, compound optimisation and pre-Phase I studies. In vivo …

[HTML][HTML] What can you see with imaging in pharmaceutical research?

ZR Lu - Molecular Pharmaceutics, 2006 - ACS Publications
The pharmaceutical research community has had a longstanding guideline that for
experimental therapeutic preclinical studies at least six animals are required for each data …

Preclinical Imaging for Laboratory Rodents

P Chaudhari - Essentials of Laboratory Animal Science: Principles …, 2021 - Springer
Laboratory animals play an important role in biomedical research and act as a backbone of
new drug research and development. Biomedical research is primarily dependent on …

Imaging in drug development with reporter mice

C Martelli, IV Libani, R Lui… - Minerva Biotecnologica, 2009 - search.proquest.com
Drug development is a time consuming and costly process, and new molecules go through
preclinical studies in a variety of experimental animals and different phases of clinical trials …

Preclinical imaging: an essential ally in modern biosciences

L Cunha, I Horvath, S Ferreira, J Lemos… - Molecular diagnosis & …, 2014 - Springer
Translational research is changing the practice of modern medicine and the way in which
health problems are approached and solved. The use of small-animal models in basic and …

[PDF][PDF] Preclinical imaging: improving translational power in oncology

T Sasser - Drug Discovery, 2016 - ddw-online.com
Imaging has long been indispensable in clinical practice, and researchers have for many
years used the same toolbox of imaging modalities as a component of their preclinical and …

Technologies: preclinical imaging for drug development

PM Matthews, R Coatney, H Alsaid, B Jucker… - Drug Discovery Today …, 2013 - Elsevier
Preclinical imaging with magnetic resonance imaging (MRI), computerised tomography
(CT), ultrasound (US), positron emission tomography (PET) or single-photon emission …

Application of biomedical imaging in drug discovery and development

ZR Lu - Pharmaceutical Research, 2007 - Springer
Drug discovery and development is a time-consuming and costly process, which may take
approximately 15 years to advance from laboratory discovery to FDA approval and require …

[HTML][HTML] In vivo Imaging in Pharmacological Research

N Beckmann, IA Kaltashov, AD Windhorst - Frontiers in pharmacology, 2017 - frontiersin.org
The discovery and development of a biologically active molecule with therapeutic properties
is an increasingly complex task, highly unpredictable at the early stages and frequently …