Lipid metabolism disturbances contribute to insulin resistance and decrease insulin sensitivity by malathion exposure in Wistar rat

MM Lasram, K Bouzid, IB Douib, A Annabi… - Drug and chemical …, 2015 - Taylor & Francis
Several studies showed that organophosphorus pesticides disturb glucose homeostasis and
can increase incidence of metabolic disorders and diabetes via insulin resistance. The …

Changes in glucose metabolism and reversion of genes expression in the liver of insulin-resistant rats exposed to malathion. The protective effects of N-acetylcysteine

MM Lasram, N El-Golli, AJ Lamine, IB Douib… - General and …, 2015 - Elsevier
Organophosphorus pesticides are known to disturb glucose homeostasis and increase
incidence of metabolic disorders and diabetes via insulin resistance. The current study …

Biochemical evidence on the potential role of organophosphates in hepatic glucose metabolism toward insulin resistance through inflammatory signaling and free …

S Mostafalou, MA Eghbal… - Toxicology and …, 2012 - journals.sagepub.com
Several studies show that organophosphate pesticides exert several effects on glucose
homeostasis. The current study investigates the influence of subchronic exposure to …

Metabolic disorders of acute exposure to malathion in adult Wistar rats

MM Lasram, AB Annabi, N El Elj, S Selmi… - Journal of Hazardous …, 2009 - Elsevier
Malathion is a widely organphosphorus insecticide used in agriculture, which shows strong
insecticidal effects. However, the use of this insecticide leads to disruption in metabolic …

Association of inflammatory response and oxidative injury in the pathogenesis of liver steatosis and insulin resistance following subchronic exposure to malathion in …

MM Lasram, IB Dhouib, K Bouzid, AJ Lamine… - Environmental …, 2014 - Elsevier
Insulin resistance and risk of type 2 diabetes are the most important complications following
exposure to organophosphorous (OPs) pesticides. Regarding the importance of liver on …

Induction of insulin resistance by malathion: Evidence for disrupted islets cells metabolism and mitochondrial dysfunction

S Pournourmohammadi, SN Ostad, E Azizi… - Pesticide biochemistry …, 2007 - Elsevier
Hyperglycemia is observed with exposure to organophosphorus (OP) pesticides. The aim of
this study was to investigate the effects of malathion on secretion of insulin from rat …

Malathion exposure modulates hypothalamic gene expression and induces dyslipedemia in Wistar rats

R Rezg, B Mornagui, M Benahmed… - Food and chemical …, 2010 - Elsevier
Exposure to organophosphate (OP) pesticides is virtually ubiquitous. These inevitable
agents are neurotoxicants, but recent evidence also points to lasting effects on carbohydrate …

On the biochemical and molecular mechanisms by which malathion induces dysfunction in pancreatic islets in vivo and in vitro

A Nili-Ahmadabadi, N Pourkhalili, S Fouladdel… - Pesticide Biochemistry …, 2013 - Elsevier
Recent studies showed that organophosphorus pesticides can increase incidence of
metabolic disorders and diabetes. Considering the importance of pancreas in regulating …

Effects of exposure to malathion on blood glucose concentration: a meta-analysis

MA Ramirez-Vargas, E Flores-Alfaro… - … Science and Pollution …, 2018 - Springer
Exposure to malathion (an organophosphate pesticide widely used around the world) has
been associated with alterations in blood glucose concentration in animal models. However …

Effects of inhalational exposure of malathion on blood glucose and antioxidants level in Wistar albino rats

A Ruckmani, PG Nayar, VGR Konda… - Research Journal of …, 2011 - search.proquest.com
The adverse effects of spraying pesticides to the ecosystem are being widely studied. While
the effects of their oral and topical exposure have been reported, especially on carbohydrate …