Background: Effective cancer therapy is still a great challenge for modern medical research
due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, and the …

Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise
summary of nanotechnological interventions for cancer management. It highlights the basics …

Highlights•This article discusses the factors that contribute to helping the cancer cells
acquire the phenomenon of multiple drug resistance (MDR).•Critical molecular targets …

The justification of cancer nanomedicine relies on enhanced permeation (EP) and retention
(R) effect and the capability of intracellular targeting due primarily to size after internalization …

Nanomaterials, with their unique size-dependent physical and chemical properties, have
shown promising advantages as drug and gene delivery vehicles, ultra-sensitive …

Introduction: Drug resistance is the major obstacle impeding the efficacy of
chemotherapeutic agents. Although numerous drug delivery techniques have been …

Highlights•A systematic review on how new generation molecular nanomedicine allows
chemoresistant cancer management.•Recent developments in molecular targeting …

The tumor microenvironment (TME) is a very cunning system that enables tumor cells to
escape death post‐traditional antitumor treatments through the comprehensive effect of …

Drug resistance to conventional antitumor drugs represents one of the major causes of
treatment failure in patients affected by tumors. Two main types of drug resistance to …