Nutritional rickets, caused by vitamin D and/or calcium deficiency is by far the most common
cause of rickets. In resource-limited settings, it is therefore not uncommon to treat rickets with …

Rickets is a common bone disease worldwide that is associated with disturbances in
calcium and phosphate homeostasis and can lead to short stature and joint deformities …

Rickets is a condition that has been recognized for many centuries and is due to defective
mineralization of the growth plate in growing children. This defect compromises the …

Abstract Fibroblast growth factor-23 (FGF23) is central to phosphate homeostasis. The
author examined if blood levels of FGF23 allow discrimination of classic hypophosphatemic …

Rickets is a childhood disorder of decreased mineralization of bone tissue. It is either
calciopenic or phosphopenic, according to the deficient mineral. Calcium, phosphate, and …

A girl with autosomal dominant hypophosphatemic rickets, presented with clinical,
radiological and laboratory signs of rickets at the age of 11 months. She showed a good …

Background Primary hypophosphatemic syndromes are a heterogeneous group of rare
diseases. In recent years, fibroblast growth factor 23 (FGF23) has been postulated as a …

The common denominator for all types of rickets is hypophosphatemia, leading to
inadequate supply of the mineral to the growing bone. Hypophosphatemia can result from …

Hypophosphatemic rickets is caused by renal phosphate wasting that is most commonly due
to X-linked dominant mutations in PHEX. PHEX mutations cause hypophosphatemia …

In children, hypophosphatemic rickets (HR) is revealed by delayed walking, waddling gait,
leg bowing, enlarged cartilages, bone pain, craniostenosis, spontaneous dental abscesses …