This review summarises the major developments of macroporous bioceramics used mainly
for repairing bone defects. Porous bioceramics have been receiving attention ever since …

This paper describes an investigation into the influence of microporosity on early
osseointegration within porous hydroxyapatite scaffolds. Two batches of phase pure porous …

During the last decades, different materials of both natural and synthetic origin have been
developed with the aim of inducing and controlling osteogenic differentiation of …

Abstract Zirconia (ZrO 2) and alumina (Al 2 O 3) based ceramics are widely used for load-
bearing applications in bone repair due to their excellent mechanical properties and …

Previously, a strong and bioactive ceramic scaffold consisting of a porous zirconia body
coated with apatite double layers (fluorapatite (FA) as an inner layer and hydroxyapatite …

The role of the material composition, porosity and surface topography of scaffolds for
promotion of osteogenesis and osseointegration is not fully understood. The aim of the …

Tissue engineering has acquired remarkable attention as an alternative strategy to treat and
restore bone defects during recent years. A scaffold is a fundamental component for tissue …

Biomimetics takes advantage of natural strategies for the solution of technological problems,
including the proper design of biomaterials. Living bone exhibits a hierarchical porosity with …

The interconnections in a porous biomaterial are the pathways between the pores. They
conduct cells and vessels between pores. Thus they favour bone ingrowth inside ceramics …

Bone tissue has a strong potential for regeneration after fractures or the appearance of bony
defects. Autogenous bone grafting, which is biocompatible, osteoconductive, angiogenic …