Sweet perception promotes food intake, whereas that of bitterness is inhibitory. Surprisingly,
the expression of sweet G protein-coupled taste receptor (GPCTR) subunits (T1R2 and …

Brain glucosensing is essential for normal body glucose homeostasis and neuronal function.
However, the exact signaling mechanisms involved in the neuronal sensing of extracellular …

Taste perception on the tongue is essential to help us to identify nutritious or potential toxic
food substances. Emerging evidence has demonstrated the expression and function of bitter …

The perception of sweet taste is mediated by the T1R2/T1R3 receptor, which is expressed in
the oral cavity, wherein it provides input on the caloric and macronutrient contents of …

Sweet taste receptors are a heterodimer composed of taste type 1 receptor 2 (T1R2) and
taste type 1 receptor 3 (T1R3) that senses sweet taste in taste buds. More recently, sweet …

Sweet taste receptors (STRs) on the tongue mediate gustatory sweet sensing, but their
expression in the gut, pancreas, and adipose tissue suggests a physiological contribution to …

Sweet taste transduction involves taste receptor type 1, member 2 (T1R2), taste receptor
type 1, member 3 (T1R3), gustducin, and TRPM5. Because knockout (KO) mice lacking …

Obesity is caused by an imbalance between food intake and energy expenditure. In recent
decades the gastrointestinal tract has received growing attention as a control parameter for …

Intestinal chemosensory signaling pathways involving the gustatory G-protein, gustducin,
and bitter taste receptors (TAS2R) have been implicated in gut hormone release. Alterations …

The sweet taste is of immense interest to scientists and has been intensively studied during
the last two decades. However, the sweet preference modification and the related …