Timing and extent of surgery in symptomatic and asymptomatic neuroendocrine tumors of the pancreas in MEN 1

G Åkerström, O Hessman, B Skogseid - Langenbeck's archives of surgery, 2002 - Springer
Pancreaticoduodenal tumors develop in a majority of patients with multiple endocrine
neoplasia type 1 (MEN 1) and have a pronounced effect on life expectancy as the principal …

Causes of death and prognostic factors in multiple endocrine neoplasia type 1: a prospective study: comparison of 106 MEN1/Zollinger-Ellison syndrome patients with …

T Ito, H Igarashi, H Uehara, MJ Berna, RT Jensen - Medicine, 2013 - journals.lww.com
Multiple endocrine neoplasia type 1 (MEN1) is classically characterized by the development
of functional or nonfunctional hyperplasia or tumors in endocrine tissues (parathyroid …

Multiple endocrine neoplasia type 1: new clinical and basic findings

DH Schussheim, MC Skarulis, SK Agarwal… - Trends in Endocrinology …, 2001 - cell.com
Multiple endocrine neoplasia type 1 (MEN1) provides a prime example of how a rare
disease can advance our understanding of basic cell biology, neoplasia and common …

Multiple endocrine neoplasia type 1 and Zollinger-Ellison syndrome: a prospective study of 107 cases and comparison with 1009 cases from the literature

F Gibril, M Schumann, A Pace, RT Jensen - Medicine, 2004 - journals.lww.com
In patients with multiple endocrine neoplasia type 1 (MEN1), the most common functional
pancreatic endocrine tumor (PET) syndrome is Zollinger-Ellison syndrome (ZES). ZES has …

Long-term follow-up of MEN1 patients who do not have initial surgery for small≤ 2 cm nonfunctioning pancreatic neuroendocrine tumors, an AFCE and GTE study …

F Triponez, SM Sadowski, F Pattou… - Annals of …, 2018 - journals.lww.com
Objective: To report long-term follow-up of patients with multiple endocrine neoplasia type 1
(MEN1) and nonfunctioning pancreatic neuroendocrine tumors (NF-PET). Background …

JNETS clinical practice guidelines for gastroenteropancreatic neuroendocrine neoplasms: diagnosis, treatment, and follow-up: a synopsis

T Ito, T Masui, I Komoto, R Doi, RY Osamura… - Journal of …, 2021 - Springer
Neuroendocrine neoplasms (NENs) are rare neoplasms that occur in various organs and
present with diverse clinical manifestations. Pathological classification is important in the …

Multiple endocrine neoplasia type 1: latest insights

ML Brandi, SK Agarwal, ND Perrier, KE Lines… - Endocrine …, 2021 - academic.oup.com
Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome that is inherited in an
autosomal dominant pattern, is continuing to raise great interest for endocrinology …

Pancreaticoduodenal endocrine tumors in multiple endocrine neoplasia type 1: surgery or surveillance?

DK Bartsch, P Langer, A Wild, T Schilling, I Celik… - Surgery, 2000 - Elsevier
Background. The management of pancreaticoduodenal endocrine tumors (PETs) remains
controversial in multiple endocrine neoplasia type 1 (MEN 1). Methods. Twenty-one patients …

Recapitulation of Pancreatic Neuroendocrine Tumors in Human Multiple Endocrine Neoplasia Type I Syndrome via Pdx1-Directed Inactivation of Men1

HCJ Shen, M He, A Powell, A Adem, D Lorang… - Cancer research, 2009 - AACR
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal syndrome caused by mutations
in the MEN1 tumor suppressor gene. Whereas the protein product of MEN1, menin, is …

Prognostic factors for the outcome of nonfunctioning pancreatic neuroendocrine tumors in MEN1: a systematic review of literature

SM Sadowski, CRC Pieterman… - Endocrine-related …, 2020 - erc.bioscientifica.com
Metastatic duodenopancreatic neuro-endocrine tumors (dpNETs) are the most important
disease-related cause of death in patients with multiple endocrine neoplasia type 1 (MEN1) …