Background: Both pregnant women and providers of obstetric care are aware of the rapid
advances in noninvasive prenatal diagnosis (NIPD) of fetal trisomies, and appear to look …

Introduction The aim of this study was to review the performance of non‐invasive prenatal
testing (NIPT) for detection of trisomy 21, 18 and 13 (T21, T18 and T13) in a general …

BACKGROUND Research on noninvasive prenatal testing (NIPT) of fetal trisomy 21 is
developing fast. Commercial tests have become available. To provide an up-to-date …

Objective Evaluate noninvasive prenatal testing (NIPT) with cell‐free DNA as a screening
method for trisomies 21, 18, and 13 in an obstetrical clinical practice setting. Methods …

Objective By‐the‐book implementation of non‐invasive prenatal test and clinical validation
for trisomy 21. Study Design Publicly funded prospective study of 225 cases. Women at risk …

OBJECTIVE: We sought to evaluate a multiplexed massively parallel shotgun sequencing
assay for noninvasive trisomy 21 detection using circulating cell-free fetal DNA. STUDY …

Since the existence of cell-free fetal DNA (cff-DNA) in maternal circulation was discovered, it
has been identified as a promising source of fetal genetic material in the development of …

Objective Maternal characteristics and neonatal outcomes associated with cell-free DNA
(cfDNA) results were analysed retrospectively to assess the details of false-positive and …

Current prenatal diagnosis for fetal aneuploidies (including trisomy 21 [T21]) generally relies
on an initial biochemical serum-based noninvasive prenatal testing (NIPT) after which …

Background This study was an evaluation of the role of noninvasive prenatal testing (NIPT)
in the detection of trisomy 7 in prenatal diagnosis. Method A total of 35 consecutive cases …