Virological efficacy and emergence of drug resistance in adults on antiretroviral treatment in rural Tanzania

A Johannessen, E Naman, SL Kivuyo, MJ Kasubi… - BMC infectious …, 2009 - Springer
Background Virological response to antiretroviral treatment (ART) in rural Africa is poorly
described. We examined virological efficacy and emergence of drug resistance in adults …

Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital

C Bratholm, A Johannessen, E Naman… - Journal of …, 2010 - academic.oup.com
Objectives To assess long-term virological efficacy and the emergence of drug resistance in
children who receive antiretroviral treatment (ART) in rural Tanzania. Patients and methods …

Drug resistance in HIV patients with virological failure or slow virological response to antiretroviral therapy in Ethiopia

A Abdissa, D Yilma, J Fonager, AM Audelin… - BMC infectious …, 2014 - Springer
Background The ongoing scale-up of antiretroviral therapy (ART) in sub-Saharan Africa has
prompted the interest in surveillance of transmitted and acquired HIV drug resistance …

High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa

J Manasa, RJ Lessells, A Skingsley, KK Naidu… - PloS one, 2013 - journals.plos.org
Objective To determine the frequency and patterns of acquired antiretroviral drug resistance
in a rural primary health care programme in South Africa. Design Cross-sectional study …

Virological outcome and patterns of HIV‐1 drug resistance in patients with 36 months' antiretroviral therapy experience in Cameroon

AF Aghokeng, C Kouanfack… - Journal of the …, 2013 - Wiley Online Library
Introduction The current expansion of antiretroviral treatment (ART) in the developing world
without routine virological monitoring still raises concerns on the outcome of the strategy in …

From antiretroviral therapy access to provision of third line regimens: evidence of HIV Drug resistance mutations to first and second line regimens among Ugandan …

I Namakoola, I Kasamba, BN Mayanja, P Kazooba… - BMC research …, 2016 - Springer
Background HIV care programs in resource-limited settings have hitherto concentrated on
antiretroviral therapy (ART) access, but HIV drug resistance is emerging. In a cross-sectional …

Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya

K Steegen, S Luchters, K Dauwe, J Reynaerts… - AIDS research and …, 2009 - Springer
Access to antiretroviral therapy (ART) is increasing in resource-limited settings (RLS) and
can successfully reduce HIV-related morbidity and mortality. However, virologic failure and …

Virologic failure and human immunodeficiency virus drug resistance in rural Cameroon with regard to the UNAIDS 90-90-90 treatment targets

C Boullé, E Guichet, C Kouanfack… - Open Forum …, 2016 - academic.oup.com
Abstract Background In rural Africa, data on virologic effectiveness of antiretroviral treatment
(ART) are not sufficient to assess the gap with the UNAIDS 90-90-90 treatment targets. We …

Development of HIV drug resistance in a cohort of adults on first-line antiretroviral therapy in Tanzania during the stavudine era

RZ Sangeda, P Gómes, SY Rhee, F Mosha… - Microbiology …, 2021 - mdpi.com
As more HIV patients start combination antiretroviral therapy (cART), the emergence of HIV
drug resistance (HIVDR) is inevitable. This will have consequences for the transmission of …

Virologic versus immunologic monitoring and the rate of accumulated genotypic resistance to first-line antiretroviral drugs in Uganda

SJ Reynolds, H Sendagire, K Newell… - BMC infectious …, 2012 - Springer
Background Viral load monitoring (VLM) to identify individuals failing antiretroviral therapy
(ART) is not widely available in resource-limited settings. We compared the genotypic …