Membranous nephropathy: mechanistic insights and therapeutic perspectives

MR Hua, YL Zhao, JZ Yang, L Zou, YY Zhao… - International …, 2023 - Elsevier
Membranous nephropathy (MN) is one of the most common causes of non-diabetic
nephrotic syndrome in adults. About 80% of cases are renal limited (primary MN) and 20 …

Membranous nephropathy: new pathogenic mechanisms and their clinical implications

E Hoxha, L Reinhard, RAK Stahl - Nature Reviews Nephrology, 2022 - nature.com
Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

New ways of understanding membranous nephropathy

H Trujillo, M Alonso, M Praga - Nephron, 2020 - karger.com
Background: In the last decade, great advances have been made in the field of membranous
nephropathy (MN). The autoimmune nature of the disease has been confirmed with the …

Membranous nephropathy: Clearer pathology and mechanisms identify potential strategies for treatment

EYM Chung, YM Wang, K Keung, M Hu… - Frontiers in …, 2022 - frontiersin.org
Primary membranous nephropathy (PMN) is one of the common causes of adult-onset
nephrotic syndrome and is characterized by autoantibodies against podocyte antigens …

Immunopathogenesis of membranous nephropathy: an update

H Debiec, P Ronco - Seminars in immunopathology, 2014 - Springer
Membranous nephropathy (MN) is a non-inflammatory organ-specific autoimmune disease
which affects the kidney glomerulus, resulting in the formation of immune deposits on the …

Membranous nephropathy: approaches to treatment

AS Bomback, FC Fervenza - American journal of nephrology, 2018 - karger.com
Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in
adults. This review focuses on mechanisms involved in the pathogenesis of MN and …

Cytokines network in primary membranous nephropathy

Q Zhao, H Dai, Y Hu, H Jiang, Z Feng, W Liu… - International …, 2022 - Elsevier
There have been extensive studies on the immunological mechanism of primary
membranous nephropathy (PMN). Autoantibodies, being the end product of humoral auto …

Membranous nephropathy

P Ronco, L Beck, H Debiec, FC Fervenza… - Nature reviews Disease …, 2021 - nature.com
Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …

[HTML][HTML] Immunology of membranous nephropathy

S Akiyama, E Imai, S Maruyama - F1000Research, 2019 - ncbi.nlm.nih.gov
Accounting for about 20 to 50% of cases of primary nephrotic syndrome, membranous
nephropathy (MN) is the leading cause of nephrotic syndrome in adults. A rat model created …

[PDF][PDF] Complement pathways in membranous nephropathy: complex and multifactorial

V Brglez, S Boyer-Suavet, B Seitz-Polski - Kidney International Reports, 2020 - Elsevier
Membranous nephropathy (MN) is a rare, but severe autoimmune kidney disease and a
major cause of nephrotic syndrome in adults. Clinically defined by nephrotic syndrome …