Objectives Bisphosphonates are widely used to treat bone diseases such as osteoporosis.
However, they may cause osteonecrosis of the jaw. Here, we investigated whether in vivo …

Bisphosphonates have been associated with osteonecrosis of the jaw. The purpose of this
study was to examine the effect of a potent bisphosphonate, zoledronic acid (ZA) on …

OBJECTIVE: The aim of this study was to histopathologically evaluate the effects of
pamidronate and zoledronate on the mandible in an animal model. STUDY DESIGN: Sixty …

Bisphosphonates (BPs) have been extensively used for management of bone diseases with
pathologically high resorption. Despite the great clinical benefits, a severe complication …

Objective Bisphosphonate‐related osteonecrosis of the jaw is a common complication with
defective wound healing of oral mucosa and frequently occurs in patients receiving …

Osteonecrosis of the jaw (ONJ) is an adverse effect of bisphosphonate treatment that has
become the subject of increasing investigations, in particular due to its poorly understood …

Background This work aimed at determining whether bisphosphonate therapy produces a
sufficient condition for jaw osteonecrosis after tooth extraction. Methods Rats were allocated …

J Oral Pathol Med (2012) 41: 788–792 Background: Osteonecrosis of the jaw (ONJ) is a
chronic complication of bisphosphonate therapy, mainly when intravenous, in cancer …

Objective To evaluate early bony changes in an animal model of Medication-Related
Osteonecrosis of the Jaw (MRONJ) at the side of the local trauma and at the contralateral …

Objectives The intravenous injection of bisphosphonates, currently used as treatment for
osteoporosis, bone Paget's disease, multiple myeloma, or bone metastases, can cause jaw …