Bisphosphonates affect migration ability and cell viability of HUVEC, fibroblasts and osteoblasts in vitro

C Walter, A Pabst, T Ziebart, MO Klein… - Oral diseases, 2011 - Wiley Online Library
Oral Diseases (2011) 17, 194–199 Objectives: Bisphosphonate‐associated osteonecrosis of
the jaw (BP‐ONJ) is a side effect in patients being treated with bisphosphonates. The …

Site specific effects of zoledronic acid during tibial and mandibular fracture repair

YY Yu, S Lieu, D Hu, T Miclau, C Colnot - PloS one, 2012 - journals.plos.org
Numerous factors can affect skeletal regeneration, including the extent of bone injury,
mechanical loading, inflammation and exogenous molecules. Bisphosphonates are …

Higher bone matrix density exists in only a subset of patients with bisphosphonate-related osteonecrosis of the jaw

MR Allen, SL Ruggiero - Journal of oral and maxillofacial surgery, 2009 - Elsevier
PURPOSE: Because few treatment options exist for bisphosphonate-related osteonecrosis
of the jaw (BRONJ), developing methods of early detection and prevention is vital …

Bacterial promotion of bisphosphonate-induced osteonecrosis in Wistar rats

H Tsurushima, S Kokuryo, O Sakaguchi… - International Journal of …, 2013 - Elsevier
Clinically, bisphosphonate-related osteonecrosis (BRON) only occurs in the jaw (BRONJ).
We aimed to determine differences between the jaw and other bones, as well as the …

Immune cellular profile of bisphosphonate‐related osteonecrosis of the jaw

PG de Barros Silva, CC de Oliveira, LAC Brizeno… - Oral …, 2016 - Wiley Online Library
Objectives Characterize the cell profile and immunostaining of proinflammatory markers in
an experimental model of bisphosphonate‐related osteonecrosis of the jaw (BRONJ) …

Bisphosphonate uptake in areas of tooth extraction or periapical disease

S Cheong, S Sun, B Kang, O Bezouglaia… - Journal of Oral and …, 2014 - Elsevier
Purpose Bisphosphonates (BPs) are widely used for the management of bone diseases
such as osteoporosis and bone malignancy. However, osteonecrosis of the jaws (ONJ) is a …

Histomorphologic characteristics of bisphosphonate‐related osteonecrosis of the jaw

S Koerdt, S Dax, H Grimaldi, O Ristow… - Journal of oral …, 2014 - Wiley Online Library
Background Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a known side
effect of the therapy with bisphosphonates. No specific pathologic aspects or histological …

Oncologic doses of zoledronic acid induce osteonecrosis of the jaw‐like lesions in rice rats (Oryzomys palustris) with periodontitis

JI Aguirre, MP Akhter, DB Kimmel… - Journal of Bone and …, 2012 - academic.oup.com
Though osteonecrosis of the jaw (ONJ) is temporally‐associated with the use of nitrogen‐
containing bisphosphonates (N‐BPs), a cause‐and‐effect relationship has not yet been …

The bisphosphonate zoledronic acid regulates key angiogenesis-related genes in primary human gingival fibroblasts

EJ Ohlrich, DE Coates, MP Cullinan, TJ Milne… - Archives of oral …, 2016 - Elsevier
Background Osteonecrosis of the jaws is recognised as a serious complication for patients
receiving bisphosphonates. The anti-angiogenic effects of bisphosphonates have been …

Histopathological features of bisphosphonates related osteonecrosis of the jaw in rats with and without vitamin d supplementation

S Yanık, MH Aras, S Erkılıç, Z Bozdağ, T Demir… - Archives of oral …, 2016 - Elsevier
Objective Aim of this study was to investigate the effect of vitamin-D3 on the osteonecrosis of
bone that was induced after tooth extraction was conducted on rats that were given …