Methods The effect of proteins on hydroxyapatite-seeded crystal growth was measured by
the method of Werness et al.(1981). A beaker containing 75 mL of 1.67 mM CaCl2 and 1.00 …

The effects of potential serum inhibitors upon the growth of calcium hydroxyapatite (HAP)
crystals were studied in vivo using a pH-stat system. Whole serum caused a marked …

For a compound to inhibit potently the transformation of amorphous calcium phosphate into
hydroxyapatite, it is suggested that the minimum structural requirement is a phosphate group …

Many proteins found in mineralized tissues have been proposed to function as regulators of
the mineralization process, either as nucleators or inhibitors of hydroxyapatite (HA) …

The dependence of the kinetics of crystal growth of hydroxyapatite, HA, on concentration of
seeds and degree of solution supersaturation is examined. Empirical relations are obtained …

A chromatography column containing hydroxyapatite beads was used to study the effect of
different proteins on the rate of hydroxyapatite dissolution. The four phosphoproteins tested …

The formation of crystalline calcium hydroxyapatite from solutions of calcium and phosphate
ions and the inhibition of calcium hydroxyapatite crystal growth by polyphosphonates and …

Interaction of bone and dentin proteins with minerals is an elementary step in the regulation
of mineralization in these tissues. Adsorption of acidic non-collagenous proteins on …

Several phosphoprotein preparations (phosvitin, rat incisor and fetal calf molar dentin
phosphoproteins) all inhibit apatite growth/replication from pre-existing crystal seeds in …

Samples of hydroxyapatite with differing crystal sizes were prepared from solutions
containing labeled calcium and strontium. Analysis of these preparations and the results of …